ACS transforms to QUIN non-enzymatically

Stable Identifier
R-HSA-197187
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
Synonyms
(2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde => quinolinate + H2O + H(+), 2-amino 3-carboxymuconate semialdehyde transforms non-enzymatically to quinolinate
ReviewStatus
4/5
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ACS transforms to QUIN non-enzymatically
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Cytosolic 2-amino 3-carboxymuconate semialdehyde reacts non-enzymatically to form quinolinate and water (Colabroy & Begley 2005).
Literature References
PubMed ID Title Journal Year
15656614 The pyridine ring of NAD is formed by a nonenzymatic pericyclic reaction

Begley, TP, Colabroy, KL

J Am Chem Soc 2005
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Cross References
RHEA
Authored
Jassal, B  (2007-05-02)
Created
Jassal, B  (2007-05-02)
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