Reactome | ICAM3 [plasma membrane]

ICAM3 [plasma membrane]

Stable Identifier

R-HSA-197682

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Intercellular adhesion molecule-3 precursor, ICA3_HUMAN

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Locations in the PathwayBrowser for interactor UniProt:P11686 SFTPC

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External Reference Information

External Reference

UniProt:P32942 ICAM3

Gene Names

ICAM3

Chain

signal peptide:1-29, chain:30-547

Reference Genes

BioGPS Gene:3385 ICAM3

COSMIC (genes):ICAM3 ICAM3

CTD Gene:3385 ICAM3

dbSNP Gene:3385 ICAM3

ENSEMBL:ENSG00000076662 ICAM3

HGNC:5346 ICAM3

KEGG:hsa:3385 ICAM3

Monarch:3385 ICAM3

NCBI Gene:3385 ICAM3

OMIM:146631 ICAM3

UCSC:P32942 ICAM3

Reference Transcript

RefSeq:NM_002162.4 ICAM3

Other Identifiers

11755072_a_at

11762232_a_at

11762233_x_at

16868679

204949_PM_at

204949_at

3385

3850258

3850259

3850260

3850262

3850263

3850264

3850265

3850266

3850267

3850268

3850269

3850270

3850271

3850272

3850273

3850274

3850275

3850276

3850277

402_s_at

8033987

A_23_P164691

GE59962

GO:0005102

GO:0005178

GO:0005515

GO:0005886

GO:0006909

GO:0007155

GO:0016020

GO:0016192

GO:0043226

GO:0070062

GO:0098609

HMNXSV003005018

ILMN_2212763

PH_hs_0017146

TC19001163.hg

X69819_at

g12545399_3p_at

Participates

as a component of

CD209:ICAM3:Ca+2 [plasma membrane] (Homo sapiens)

as an input of

CD209 binds ICAM3 (Homo sapiens)

as a member of

ICAM 1-5 [plasma membrane] (Homo sapiens)

Inferred To

si:ch73-208g10.1 [plasma membrane] (Danio rerio)

ICAM3 [plasma membrane] (Bos taurus)

ICAM3 [plasma membrane] (Canis familiaris)

Cross References

RefSeq

NP_002153.2

ENSEMBL

ENSP00000160262, ENST00000160262

OpenTargets

ENSG00000076662

HPA

ENSG00000076662-ICAM3

PRO

P32942

Pharos - Targets

P32942

GlyGen

P32942

PDB

1T0P

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6PL45-2 BRICD5			0.556	3
UniProt:Q96IW7 SEC22A	3	SEC22A [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688562) SEC22A [ER to Golgi transport vesicle membrane] (R-HSA-5688560) SEC22A [endoplasmic reticulum membrane] (R-HSA-5216111)	0.556	3
UniProt:P11686 SFTPC	9	pro-SFTPC P115L [endoplasmic reticulum membrane] (R-HSA-5688352) pro-SFTPC P30L [endoplasmic reticulum membrane] (R-HSA-5688365) pro-SFTPC [endoplasmic reticulum membrane] (R-HSA-5683842) pro-SFTPC [multivesicular body lumen] (R-HSA-5685298) SFTPC [extracellular region] (R-HSA-5683685) SFTPC [clathrin-coated endocytic vesicle] (R-HSA-5686342) SFTPC [lamellar body] (R-HSA-5683717) SFTPC(24-58) [multivesicular body lumen] (R-HSA-5685899) SFTPC(59-197) [multivesicular body lumen] (R-HSA-5685871)	0.556	3
UniProt:P56851 EP3B			0.556	3
UniProt:Q9NRQ5 SMCO4			0.556	3
UniProt:P30536 TSPO	1	TSPO [mitochondrial outer membrane] (R-HSA-2980957)	0.556	3
UniProt:O14493 CLDN4	2	CLDN4 [plasma membrane] (R-HSA-419987) CLDN4 [cell junction] (R-HSA-421244)	0.556	3
UniProt:B2RUZ4 SMIM1			0.556	3
UniProt:Q9NZG7 NINJ2			0.556	3
UniProt:Q8N6F1-2 CLDN19			0.556	3
UniProt:Q8TF32 ZNF431	1	ZNF431 [nucleoplasm] (R-HSA-1247546)	0.527	2

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