Reactome | ICAM5 [plasma membrane]

ICAM5 [plasma membrane]

Stable Identifier

R-HSA-197684

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Intercellular adhesion molecule-5 precursor, ICA5_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9UMF0 ICAM5

Gene Names

ICAM5, TLCN, TLN

Chain

signal peptide:1-31, chain:32-924

Reference Genes

BioGPS Gene:7087 ICAM5

COSMIC (genes):ICAM5 ICAM5

CTD Gene:7087 ICAM5

dbSNP Gene:7087 ICAM5

ENSEMBL:ENSG00000105376 ICAM5

ENSEMBL_homo_sapiens_GENE:ENSG00000105376.5 ICAM5

HGNC:5348 ICAM5

KEGG Gene (Homo sapiens):7087 ICAM5

Monarch:7087 ICAM5

NCBI Gene:7087 ICAM5

OMIM:601852 ICAM5

UCSC:Q9UMF0 ICAM5

Reference Transcript

Other Identifiers

11734245_at

16858156

206906_PM_at

206906_at

3820470

3820471

3820474

3820477

3820478

3820479

3820480

3820482

3820483

3820484

3820486

3820487

3820489

3820490

3820491

3820492

3820493

3820497

40209_at

7087

8025621

A_23_P119143

A_24_P254079

GE81255

GO:0005178

GO:0005515

GO:0005886

GO:0006909

GO:0007155

GO:0016020

GO:0016192

GO:0034330

GO:0048856

GO:0051963

GO:0098609

GO:0098978

ILMN_1802524

PH_hs_0009117

TC19000176.hg

U72671_at

g12545403_3p_at

Participates

as a member of

ICAM 1-5 [plasma membrane] (Homo sapiens)

Inferred To

si:ch73-208g10.1 [plasma membrane] (Danio rerio)

Icam5 [plasma membrane] (Mus musculus)

Icam5 [plasma membrane] (Rattus norvegicus)

ICAM5 [plasma membrane] (Bos taurus)

ICAM5 [plasma membrane] (Canis familiaris)

ICAM5 [plasma membrane] (Sus scrofa)

Cross References

RefSeq

NP_003250.3, XP_011526531.1

OpenTargets

ENSG00000105376

GeneCards

Q9UMF0

HPA

ENSG00000105376-ICAM5

Ensembl

ENSP00000221980, ENST00000221980, ENSG00000105376

PRO

Q9UMF0

Pharos - Targets

Q9UMF0

PDB

4OI9, 3BN3, 4OIB, 4OIA

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P05094	3	ACTN1 [extracellular region] (R-GGA-349722) ACTN1 [platelet alpha granule lumen] (R-GGA-349724) ACTN1 [cytosol] (R-GGA-354096)	0.602	3
UniProt:Q9BRX5 GINS3	1	GINS3 [nucleoplasm] (R-HSA-5688046)	0.556	3
UniProt:O75528 TADA3	1	TADA3 [nucleoplasm] (R-HSA-3322966)	0.556	3
UniProt:Q8WY64 MYLIP	1	MYLIP [cytosol] (R-HSA-8850908)	0.556	3
UniProt:P13196 ALAS1	2	PXLP-ALAS1 [mitochondrial matrix] (R-HSA-1022086) ALAS1 [mitochondrial matrix] (R-HSA-189438)	0.556	3
UniProt:P02795 MT2A	1	MT2A [cytosol] (R-HSA-1031707)	0.556	3
UniProt:P05067 APP	20	APP(18-770) [trans-Golgi network membrane] (R-HSA-5229136) APP-C99 [cytosol] (R-HSA-9617603) APP(18-770) [extracellular region] (R-HSA-49335) APP(18-770) [platelet alpha granule lumen] (R-HSA-139835) APP(18-687) [extracellular region] (R-HSA-9010033) APP(688-770) [plasma membrane] (R-HSA-9010028) APP(18-770) [Golgi lumen] (R-HSA-8871509) APP(18-770) [plasma membrane] (R-HSA-9010038) APP(18-671) [endosome lumen] (R-HSA-5693003) APP(714-770) [endosome lumen] (R-HSA-6783325) APP(712-770) [endosome lumen] (R-HSA-6783331) APP(672-770) [endosome lumen] (R-HSA-9010082) APP(672-713) [endosome lumen] (R-HSA-5692993) APP(672-711) [endosome lumen] (R-HSA-6783333) APP(18-770) [endosome lumen] (R-HSA-5229077) p-APP [endoplasmic reticulum lumen] (R-HSA-8957012) APP [endoplasmic reticulum lumen] (R-HSA-8956696) APP(672-711) [extracellular region] (R-HSA-976740) APP(672-711) [cytosol] (R-HSA-877188) APP(672-713) [extracellular region] (R-HSA-879340)	0.556	3
UniProt:Q13887 KLF5	1	KLF5 [nucleoplasm] (R-HSA-381279)	0.556	3

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