Reactome | SIGLEC6 [plasma membrane]

SIGLEC6 [plasma membrane]

Stable Identifier

R-HSA-197708

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Sialic acid binding Ig-like lectin 6 precursor, SIL6_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O43699 SIGLEC6

Gene Names

SIGLEC6, CD33L, CD33L1, OBBP1

Chain

signal peptide:1-26, chain:27-453

Reference Genes

BioGPS Gene:946 SIGLEC6

COSMIC (genes):SIGLEC6 SIGLEC6

CTD Gene:946 SIGLEC6

dbSNP Gene:946 SIGLEC6

ENSEMBL:ENSG00000105492 SIGLEC6

HGNC:10875 SIGLEC6

KEGG:hsa:946 SIGLEC6

Monarch:946 SIGLEC6

NCBI Gene:946 SIGLEC6

OMIM:604405 SIGLEC6

UCSC:O43699 SIGLEC6

Reference Transcript

Participates

as a candidate of

SIGLEC [plasma membrane] (Homo sapiens)

Inferred To

SIGLEC6 [plasma membrane] (Bos taurus)

SIGLEC6 [plasma membrane] (Canis familiaris)

SIGLEC6 [plasma membrane] (Sus scrofa)

XB5961956 [plasma membrane] (Xenopus tropicalis)

LOC110261034 [plasma membrane] (Sus scrofa)

siglecl2 [plasma membrane] (Xenopus tropicalis)

LOC100138951 [plasma membrane] (Bos taurus)

Siglec5 [plasma membrane] (Mus musculus)

Siglec5 [plasma membrane] (Rattus norvegicus)

Cd33 [plasma membrane] (Mus musculus)

Cd33 [plasma membrane] (Rattus norvegicus)

LOC618463 [plasma membrane] (Bos taurus)

mag [plasma membrane] (Danio rerio)

Siglech [plasma membrane] (Mus musculus)

Siglech [plasma membrane] (Rattus norvegicus)

Homologues of SIGLEC6 [plasma membrane] (Bos taurus)

Homologues of SIGLEC6 [plasma membrane] (Canis familiaris)

Homologues of SIGLEC6 [plasma membrane] (Mus musculus)

Homologues of SIGLEC6 [plasma membrane] (Rattus norvegicus)

Homologues of SIGLEC6 [plasma membrane] (Sus scrofa)

Homologues of SIGLEC6 [plasma membrane] (Xenopus tropicalis)

LOC100515551 [plasma membrane] (Sus scrofa)

LOC484343 [plasma membrane] (Canis familiaris)

LOC100686511 [plasma membrane] (Canis familiaris)

Cross References

RefSeq

NP_001171019.1, NP_001171020.1, NP_001236.4, NP_001171018.1, NP_942143.3, NP_942142.3

Guide to Pharmacology - Targets

3301

ENSEMBL

ENSP00000345907, ENST00000436458, ENSP00000401502, ENSP00000353071, ENST00000359982, ENST00000391797, ENSP00000344064, ENSP00000410679, ENSP00000375674, ENST00000425629, ENSG00000105492, ENST00000343300, ENST00000346477

OpenTargets

ENSG00000105492

GeneCards

SIGLEC6

HPA

ENSG00000105492-SIGLEC6

PRO

O43699

Pharos - Targets

O43699

GlyGen

O43699

HMDB Protein

HMDBP14228

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14192 FHL2	1	FHL2 [nucleoplasm] (R-HSA-561161)	0.556	3

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