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SIGLEC5 [plasma membrane]
Stable Identifier
R-HSA-197711
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Sialic acid binding Ig-like lectin 5 precursor, SIL5_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Homo sapiens)
Sialic acid binds SIGLEC (Homo sapiens)
SIGLEC [plasma membrane] (Homo sapiens)
SIGLEC5 [plasma membrane] (Homo sapiens)
SIGLEC:sialic acid [plasma membrane] (Homo sapiens)
SIGLEC [plasma membrane] (Homo sapiens)
SIGLEC5 [plasma membrane] (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of ficolin-rich granule membrane proteins (Homo sapiens)
Ficolin-rich granule membrane proteins [plasma membrane] (Homo sapiens)
SIGLEC5 [plasma membrane] (Homo sapiens)
Exocytosis of secretory granule membrane proteins (Homo sapiens)
Secretory granule membrane proteins [plasma membrane] (Homo sapiens)
SIGLEC5 [plasma membrane] (Homo sapiens)
Exocytosis of tertiary granule membrane proteins (Homo sapiens)
Tertiary granule membrane proteins [plasma membrane] (Homo sapiens)
SIGLEC5 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O15389 SIGLEC5
Gene Names
SIGLEC5, CD33L2, OBBP2
Chain
signal peptide:1-16, chain:17-551
Reference Genes
BioGPS Gene:8778 SIGLEC5
COSMIC (genes):SIGLEC5 SIGLEC5
CTD Gene:8778 SIGLEC5
dbSNP Gene:8778 SIGLEC5
ENSEMBL:ENSG00000268500 SIGLEC5
ENSEMBL_homo_sapiens_GENE:ENSG00000268500.7 SIGLEC5
HGNC:10874 SIGLEC5
KEGG Gene (Homo sapiens):8778 SIGLEC5
Monarch:8778 SIGLEC5
NCBI Gene:8778 SIGLEC5
OMIM:604200 SIGLEC5
UCSC:O15389 SIGLEC5
Reference Transcript
RefSeq:NM_003830.3 SIGLEC5
Other Identifiers
11729739_at
16874911
220000_PM_at
220000_at
3839678
3869155
3869157
3869159
3869160
3869161
3869165
3869166
3869167
3869168
3869169
3869170
3869171
3869172
3869173
3869174
3869175
3869176
3869192
3869193
3869194
8038877
8778
90196_at
A_24_P48539
GE58313
GO:0005515
GO:0005886
GO:0007155
GO:0016020
GO:0030246
GO:0030667
GO:0031410
GO:0033691
GO:0043226
GO:0070821
GO:0101003
HMNXSV003018737
HMNXSV003031195
ILMN_1652381
ILMN_1740298
PH_hs_0006411
TC19001784.hg
g4502658_3p_at
Participates
as a candidate of
SIGLEC [plasma membrane] (Homo sapiens)
as a member of
Ficolin-rich granule membrane proteins [plasma membrane] (Homo sapiens)
Tertiary granule membrane proteins [plasma membrane] (Homo sapiens)
Secretory granule membrane proteins [plasma membrane] (Homo sapiens)
Other forms of this molecule
SIGLEC5 [ficolin-1-rich granule membrane]
SIGLEC5 [tertiary granule membrane]
SIGLEC5 [secretory granule membrane]
Inferred To
LOC112442215 [plasma membrane]
(Bos taurus)
LOC476396 [plasma membrane]
(Canis familiaris)
XB5961956 [plasma membrane]
(Xenopus tropicalis)
mag [plasma membrane]
(Danio rerio)
siglecl2 [plasma membrane]
(Xenopus tropicalis)
SIGLEC5 [plasma membrane]
(Sus scrofa)
Homologues of SIGLEC5 [plasma membrane]
(Xenopus tropicalis)
Cross References
RefSeq
NP_003821.1
OpenTargets
ENSG00000105501
HPA
ENSG00000268500-SIGLEC5
GeneCards
O15389
Ensembl
ENSP00000507738
,
ENSG00000268500
,
ENST00000683636
PRO
O15389
Pharos - Targets
O15389
Orphanet
24901
HMDB Protein
HMDBP14227
PDB
2ZG1
,
2ZG2
,
2ZG3
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O00206 TLR4
2
TLR4 [endosome membrane]
(R-HSA-2201285)
2xN4GlycoAsn-TLR4 [plasma membrane]
(R-HSA-166045)
0.544
2
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