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NRCAM [plasma membrane]
Stable Identifier
R-HSA-197758
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
NrCAM, Neuronal cell adhesion molecule precursor, NRCA_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
L1CAM interactions (Homo sapiens)
Interaction between L1 and Ankyrins (Homo sapiens)
Ankyrins link voltage-gated sodium and potassium channels to spectrin and L1 (Homo sapiens)
NFASC:NRCAM:ANK1-3:SPTA:SPTB:F-actin [plasma membrane] (Homo sapiens)
NFASC:NRCAM [plasma membrane] (Homo sapiens)
NRCAM [plasma membrane] (Homo sapiens)
NFASC:NRCAM:ANK1-3:SPTA:SPTB:F-actin:KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
NFASC:NRCAM:ANK1-3:SPTA:SPTB:F-actin [plasma membrane] (Homo sapiens)
NFASC:NRCAM [plasma membrane] (Homo sapiens)
NRCAM [plasma membrane] (Homo sapiens)
Neurofascin interactions (Homo sapiens)
Neurofascin and NrCAM heterodimerization (Homo sapiens)
NFASC:NRCAM [plasma membrane] (Homo sapiens)
NRCAM [plasma membrane] (Homo sapiens)
NRCAM [plasma membrane] (Homo sapiens)
NrCAM interactions (Homo sapiens)
NrCAM binds Ankyrin-G (Homo sapiens)
NRCAM [plasma membrane] (Homo sapiens)
NrCAM:Ankyrin-G [plasma membrane] (Homo sapiens)
NRCAM [plasma membrane] (Homo sapiens)
NrCAM binds Neuropilin-2 (Homo sapiens)
NRCAM [plasma membrane] (Homo sapiens)
NRP2:NrCAM [plasma membrane] (Homo sapiens)
NRCAM [plasma membrane] (Homo sapiens)
NrCAM binds axonin-1 (Homo sapiens)
NRCAM [plasma membrane] (Homo sapiens)
NrCAM:Axonin-1 [plasma membrane] (Homo sapiens)
NRCAM [plasma membrane] (Homo sapiens)
NrCAM binds synapse-associated proteins (Homo sapiens)
NRCAM [plasma membrane] (Homo sapiens)
NrCAM:SAP members [plasma membrane] (Homo sapiens)
NRCAM [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q92823 NRCAM
Gene Names
NRCAM, KIAA0343
Chain
signal peptide:1-24, chain:25-1304
Reference Genes
BioGPS Gene:4897 NRCAM
COSMIC - genes:NRCAM NRCAM
CTD Gene:4897 NRCAM
dbSNP Gene:4897 NRCAM
ENSEMBL:ENSG00000091129 NRCAM
HGNC:7994 NRCAM
KEGG:hsa:4897 NRCAM
Monarch:4897 NRCAM
NCBI Gene:4897 NRCAM
OMIM:601581 NRCAM
UCSC:Q92823 NRCAM
Reference Transcript
RefSeq:NM_001371155.1 NRCAM
RefSeq:NM_001371167.1 NRCAM
RefSeq:NM_001371177.1 NRCAM
RefSeq:NM_001371181.1 NRCAM
RefSeq:NM_001193582.1 NRCAM
RefSeq:NM_001371165.1 NRCAM
RefSeq:NM_001371122.1 NRCAM
RefSeq:NM_001371133.1 NRCAM
RefSeq:NM_001371151.1 NRCAM
RefSeq:NM_001371162.1 NRCAM
RefSeq:NM_001193584.2 NRCAM
RefSeq:NM_001371131.1 NRCAM
RefSeq:NM_001371171.1 NRCAM
RefSeq:XM_006716003.3 NRCAM
RefSeq:NM_001371163.1 NRCAM
RefSeq:NM_001371139.1 NRCAM
RefSeq:NM_001037132.4 NRCAM
RefSeq:NM_001371178.1 NRCAM
RefSeq:NM_001193583.2 NRCAM
RefSeq:NM_005010.4 NRCAM
Other Identifiers
11724337_s_at
11741150_a_at
11746394_a_at
11746395_x_at
11747639_a_at
17061759
204105_PM_s_at
204105_s_at
216959_PM_x_at
216959_x_at
3067475
3067477
3067479
3067480
3067481
3067482
3067483
3067484
3067485
3067487
3067488
3067490
3067492
3067494
3067498
3067499
3067504
3067507
3067508
3067511
3067513
3067514
3067516
3067517
3067519
3067520
3067521
3067522
3067523
3067524
3067525
3067535
3067536
3067537
3067538
3067539
3067540
3067542
3067544
3067545
3067546
3067547
3067548
3067549
3067551
3067552
3067553
3067568
3067572
3067579
3067580
3067581
3067591
3067594
37286_at
37287_at
37288_g_at
4897
67201_at
8142270
A_24_P252364
A_33_P3301514
GE53068
GO:0001525
GO:0001764
GO:0005515
GO:0005576
GO:0005886
GO:0007155
GO:0007409
GO:0007411
GO:0007413
GO:0007416
GO:0007417
GO:0007420
GO:0008092
GO:0008104
GO:0009897
GO:0010975
GO:0016020
GO:0019227
GO:0030424
GO:0030506
GO:0030516
GO:0031290
GO:0034113
GO:0034330
GO:0042995
GO:0043005
GO:0043194
GO:0045162
GO:0045202
GO:0045211
GO:0045666
GO:0048856
GO:0048870
GO:0050808
GO:0050877
GO:0061024
GO:0086080
GO:0098609
GO:0098631
GO:0098632
GO:0098839
GO:0098978
GO:0099175
HMNXSV003035992
HMNXSV003039673
Hs.7912.2.S1_3p_s_at
ILMN_1722809
ILMN_2411236
PH_hs_0000819
TC07001751.hg
U55258_at
g4826863_3p_s_at
Participates
as a component of
NrCAM:Axonin-1 [plasma membrane] (Homo sapiens)
NRP2:NrCAM [plasma membrane] (Homo sapiens)
NrCAM:SAP members [plasma membrane] (Homo sapiens)
NrCAM:Ankyrin-G [plasma membrane] (Homo sapiens)
NFASC:NRCAM [plasma membrane] (Homo sapiens)
as an input of
NrCAM binds axonin-1 (Homo sapiens)
NrCAM binds Neuropilin-2 (Homo sapiens)
NrCAM binds synapse-associated proteins (Homo sapiens)
NrCAM binds Ankyrin-G (Homo sapiens)
Neurofascin and NrCAM heterodimerization (Homo sapiens)
Inferred To
NRCAM [plasma membrane]
(Drosophila melanogaster)
NRCAM [plasma membrane]
(Sus scrofa)
boi [plasma membrane]
(Drosophila melanogaster)
sax-7 [plasma membrane]
(Caenorhabditis elegans)
Homologues of NRCAM [plasma membrane]
(Caenorhabditis elegans)
Homologues of NRCAM [plasma membrane]
(Drosophila melanogaster)
sax-3 [plasma membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_001032209.1
,
NP_005001.3
,
NP_001180512.1
,
NP_001358068.1
,
NP_001358110.1
,
NP_001180513.1
,
XP_006716066.1
,
NP_001358096.1
,
NP_001358062.1
,
NP_001358051.1
,
NP_001358107.1
,
NP_001358080.1
,
NP_001358094.1
,
NP_001358092.1
,
NP_001358084.1
,
NP_001358060.1
,
NP_001358091.1
,
NP_001358106.1
,
NP_001180511.1
,
NP_001358100.1
OpenTargets
ENSG00000091129
ENSEMBL
ENSG00000091129
,
ENST00000351718
,
ENST00000379024
,
ENSP00000368310
,
ENSP00000368314
,
ENSP00000325269
,
ENST00000379028
HPA
ENSG00000091129-NRCAM
GeneCards
NRCAM
PRO
Q92823
Pharos - Targets
Q92823
PDB
1UEY
,
1UEN
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q12860 CNTN1
1
CNTN1 [plasma membrane]
(R-HSA-373622)
0.704
4
UniProt:Q7Z6J6 FRMD5
0.527
2
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