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SCN2B [plasma membrane]
Stable Identifier
R-HSA-197905
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Sodium channel beta-2 subunit, CIB2_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
L1CAM interactions (Homo sapiens)
Interaction between L1 and Ankyrins (Homo sapiens)
Ankyrins link voltage-gated sodium and potassium channels to spectrin and L1 (Homo sapiens)
KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
SCNAs:SCNBs [plasma membrane] (Homo sapiens)
SCNBs [plasma membrane] (Homo sapiens)
SCN2B [plasma membrane] (Homo sapiens)
NFASC:NRCAM:ANK1-3:SPTA:SPTB:F-actin:KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
SCNAs:SCNBs [plasma membrane] (Homo sapiens)
SCNBs [plasma membrane] (Homo sapiens)
SCN2B [plasma membrane] (Homo sapiens)
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Phase 0 - rapid depolarisation (Homo sapiens)
SCNAs:SNCBs transport Na+ from extracellular region to cytosol (Homo sapiens)
SCNAs:SCNBs [plasma membrane] (Homo sapiens)
SCNBs [plasma membrane] (Homo sapiens)
SCN2B [plasma membrane] (Homo sapiens)
Sensory Perception (Homo sapiens)
Sensory perception of taste (Homo sapiens)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Homo sapiens)
SCN2A:SCN1B,2B,4B transports Na+ from the extracellular region to the cytosol (Homo sapiens)
SCN2A:SCN1B,2B,4B [plasma membrane] (Homo sapiens)
SCN1B,2B,4B [plasma membrane] (Homo sapiens)
SCN2B [plasma membrane] (Homo sapiens)
SCN3A:SCN2B,4B transports Na+ from the extracellular region to the cytosol (Homo sapiens)
SCN3A:SCN2B,4B [plasma membrane] (Homo sapiens)
SCN2B,4B [plasma membrane] (Homo sapiens)
SCN2B [plasma membrane] (Homo sapiens)
SCN9A:SCN1B,2B,4B transports Na+ from the extracellular region to the cytosol (Homo sapiens)
SCN9A:SCN1B,2B,4B [plasma membrane] (Homo sapiens)
SCN1B,2B,4B [plasma membrane] (Homo sapiens)
SCN2B [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O60939 SCN2B
Gene Names
SCN2B, UNQ326/PRO386
Chain
signal peptide:1-29, chain:30-215
Reference Genes
BioGPS Gene:6327 SCN2B
COSMIC (genes):SCN2B SCN2B
CTD Gene:6327 SCN2B
dbSNP Gene:6327 SCN2B
ENSEMBL:ENSG00000149575 SCN2B
ENSEMBL_homo_sapiens_GENE:ENSG00000149575.9 SCN2B
HGNC:10589 SCN2B
KEGG Gene (Homo sapiens):6327 SCN2B
Monarch:6327 SCN2B
NCBI Gene:6327 SCN2B
OMIM:601327 SCN2B
Reference Transcript
RefSeq:NM_004588.4 SCN2B
Other Identifiers
11727611_a_at
11727612_at
11727613_at
11727614_at
11727615_x_at
16744960
210363_PM_s_at
210363_s_at
210364_PM_at
210364_at
235225_PM_at
235225_at
3393647
3393648
3393649
3393651
3393653
3393654
3393655
3393656
3393657
3393658
3393660
3393665
3393666
3393667
34918_at
50877_at
6327
7952011
A_23_P306819
A_32_P187571
A_33_P3394699
GE479829
GE54425
GE63295
GO:0001518
GO:0003012
GO:0003013
GO:0005215
GO:0005248
GO:0005272
GO:0005886
GO:0006811
GO:0006814
GO:0007268
GO:0007399
GO:0009408
GO:0010467
GO:0016020
GO:0017080
GO:0023052
GO:0030315
GO:0034220
GO:0034702
GO:0035725
GO:0045202
GO:0046684
GO:0048856
GO:0055085
GO:0060048
GO:0060371
GO:0061337
GO:0086002
GO:0086006
GO:0086012
GO:0086091
GO:0098772
GO:0098915
GO:1902282
GO:2000649
HMNXSV003025576
HMNXSV003028200
Hs.12714.0.S1_3p_at
Hs.12714.0.S1_3p_x_at
ILMN_1676998
PH_hs_0007603
PH_hs_0037120
TC11002343.hg
g5702193_3p_a_at
g6649596_3p_x_at
Participates
as a candidate of
SCN2B,4B [plasma membrane] (Homo sapiens)
SCN1B,2B,4B [plasma membrane] (Homo sapiens)
SCNBs [plasma membrane] (Homo sapiens)
Inferred To
SCN2B [plasma membrane]
(Bos taurus)
Cross References
RefSeq
NP_004579.1
OpenTargets
ENSG00000149575
GeneCards
O60939
HPA
ENSG00000149575-SCN2B
Ensembl
ENSG00000149575
,
ENST00000278947
,
ENSP00000278947
PRO
O60939
Pharos - Targets
O60939
Orphanet
22268
HMDB Protein
HMDBP09081
PDB
6J8G
,
7XVE
,
7XVF
,
8I5G
,
5FDY
,
7W9K
,
7XM9
,
6J8H
,
8GZ1
,
8I5X
,
7W9L
,
8GZ2
,
6J8I
,
8S9B
,
8S9C
,
5FEB
,
7W9M
,
8G1A
,
7XMF
,
7W9P
,
6VRR
,
6J8J
,
8I5Y
,
7XMG
,
7W77
,
7W9T
,
8I5B
,
6J8E
,
7W7F
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