Reactome | KLRG1 [plasma membrane]

KLRG1 [plasma membrane]

Stable Identifier

R-HSA-198006

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Killer cell lectin-like receptor subfamily G member 1, Q96E93_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q96E93 KLRG1

Gene Names

KLRG1, CLEC15A, MAFA, MAFAL

Chain

chain:1-195

Reference Genes

BioGPS Gene:10219 KLRG1

COSMIC (genes):KLRG1 KLRG1

CTD Gene:10219 KLRG1

dbSNP Gene:10219 KLRG1

ENSEMBL:ENSG00000139187 KLRG1

ENSEMBL_homo_sapiens_GENE:ENSG00000139187.10 KLRG1

HGNC:6380 KLRG1

KEGG Gene (Homo sapiens):10219 KLRG1

Monarch:10219 KLRG1

NCBI Gene:10219 KLRG1

OMIM:604874 KLRG1

UCSC:Q96E93 KLRG1

Reference Transcript

Other Identifiers

10219

11735223_a_at

11735224_a_at

16748095

210288_PM_at

210288_at

3404035

3404036

3404037

3404039

3404040

3404041

3404042

3404043

3404044

3404045

34975_at

65329_at

7953835

A_14_P102332

A_23_P64898

A_24_P261760

GE476230

GE54780

GO:0002376

GO:0005515

GO:0005886

GO:0006954

GO:0006968

GO:0007166

GO:0016020

GO:0023052

GO:0030246

GO:0038023

GO:0043226

GO:0043231

GO:0045087

GO:0060089

GO:0098542

HMNXSV003014751

HMNXSV003020380

ILMN_1658399

ILMN_2124920

PH_hs_0008729

TC12000138.hg

g3421400_3p_at

Participates

as a component of

E-cadherin bound to KLRG1 [plasma membrane] (Homo sapiens)

as an input of

Epithelial cadherin binds to KLRG1 (Homo sapiens)

Cross References

RefSeq

NP_001316028.1, NP_005801.3

OpenTargets

ENSG00000139187

GeneCards

Q96E93

HPA

ENSG00000139187-KLRG1

Ensembl

ENSP00000266551, ENSP00000349477, ENSG00000139187, ENST00000266551, ENST00000356986

PRO

Q96E93

Pharos - Targets

Q96E93

PDB

3FF7

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O95214 LERL1			0.666	4
UniProt:Q6IN84 MRM1	1	MRM1 [mitochondrial matrix] (R-HSA-6793088)	0.556	3
UniProt:Q8TED1 GPX8	1	GPX8 [endoplasmic reticulum lumen] (R-HSA-3341303)	0.556	3
UniProt:Q8N205 SYNE4			0.556	3
UniProt:P16284 PECAM1	5	PECAM1 [platelet alpha granule membrane] (R-HSA-61489) PECAM1 [plasma membrane] (R-HSA-114686) PECAM1 [secretory granule membrane] (R-HSA-6804778) p-Y663,Y686-PECAM1(27-?) [plasma membrane] (R-HSA-210007) p-Y713-PECAM1 [plasma membrane] (R-HSA-9860772)	0.556	3
UniProt:O15529 GPR42			0.556	3
UniProt:P37173 TGFBR2	9	TGFBR2 Y470D [plasma membrane] (R-HSA-3640905) TGFBR2 E526Q [plasma membrane] (R-HSA-3645770) TGFBR2 D522N [plasma membrane] (R-HSA-3640907) TGFBR2 R528H [plasma membrane] (R-HSA-3640894) TGFBR2 R528C [plasma membrane] (R-HSA-3640899) TGFBR2 K128Afs3 [cytosol] (R-HSA-3642173) TGFBR2 K128Sfs35 [cytosol] (R-HSA-3642166) NEDD8-K556,K567-TGFBR2 [plasma membrane] (R-HSA-4332222) TGFBR2 [plasma membrane] (R-HSA-170842)	0.556	3
UniProt:P26715 KLRC1	1	KLRC1 [plasma membrane] (R-HSA-3006545)	0.556	3
UniProt:Q3SXY8 ARL13B	8	PolyUb-Misfolded ARL13B [lysosomal lumen] (R-HSA-9660004) PolyUb-Misfolded ARL13B [cytosol] (R-HSA-9641129) Ub-Misfolded ARL13B [cytosol] (R-HSA-9641119) Misfolded ARL13B [cytosol] (R-HSA-9640110) Misfolded ARL13B [cilium] (R-HSA-9640116) ARL13B [cilium] (R-HSA-5618181) PolyUb-Misfolded ARL13B [late endosome lumen] (R-HSA-9659986) ARL13B [plasma membrane] (R-HSA-9716787)	0.556	3

Cite Us!