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TCR chain alpha [plasma membrane]
Stable Identifier
R-HSA-198184
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Costimulation by the CD28 family (Homo sapiens)
PD-1 signaling (Homo sapiens)
Dephosphorylation of CD3-zeta by PD-1 bound phosphatases (Homo sapiens)
Antigen-bearing MHC Class II: TCR with dephosphorylated CD3 zeta chain:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with dephosphorylated CD3 zeta chain [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Homo sapiens)
TCR binds microbial lipid-based antigen via CD1 (Homo sapiens)
CD1:B2M:microbial lipid:TCR [plasma membrane] (Homo sapiens)
T-cell receptor complex [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
T-cell receptor complex [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
TCR binds self-lipid-based antigen via CD1 (Homo sapiens)
CD1:B2M:self-lipid:TCR [plasma membrane] (Homo sapiens)
T-cell receptor complex [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
T-cell receptor complex [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
TCR complex interacts with peptide antigen-presenting MHC Class I (Homo sapiens)
T-cell receptor complex with CD8 [plasma membrane] (Homo sapiens)
T-cell receptor complex [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
TCR interacting with antigen-bearing MHC Class I [plasma membrane] (Homo sapiens)
T-cell receptor complex with CD8 [plasma membrane] (Homo sapiens)
T-cell receptor complex [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
TCR signaling (Homo sapiens)
Downstream TCR signaling (Homo sapiens)
Change of PKC theta conformation (Homo sapiens)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Homo sapiens)
T-cell receptor complex [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Generation of second messenger molecules (Homo sapiens)
Phosphorylation of PLC-gamma1 (Homo sapiens)
ZAP-70 and ITK tyrosine kinases [plasma membrane] (Homo sapiens)
Activated ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Phosphorylation of SLP-76 (Homo sapiens)
Activated ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Phosphorylation of TBSMs in LAT (Homo sapiens)
Activated ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Phosphorylation of CD3 and TCR zeta chains (Homo sapiens)
Activation of Lck (Homo sapiens)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Homo sapiens)
T-cell receptor complex [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Homo sapiens)
T-cell receptor complex [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Dephosphorylation of Lck-pY505 by CD45 (Homo sapiens)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Homo sapiens)
T-cell receptor complex [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Homo sapiens)
T-cell receptor complex [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Inactivation of LCK by PTPN22 (Homo sapiens)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Homo sapiens)
T-cell receptor complex [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Homo sapiens)
T-cell receptor complex [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Inactivation of Lck by Csk (Homo sapiens)
Antigen-bearing MHC Class II : TCR complex:CD4:Lck [plasma membrane] (Homo sapiens)
T-cell receptor complex [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II : TCR complex:CD4:p-Lck(Y505) [plasma membrane] (Homo sapiens)
T-cell receptor complex [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Phosphorylation of ITAM motifs in CD3 complexes (Homo sapiens)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Homo sapiens)
T-cell receptor complex [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Translocation of ZAP-70 to Immunological synapse (Homo sapiens)
Activation of ZAP-70 (Homo sapiens)
Activated ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
phospho tyrosine ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
PTPN22 dephosphorylates ZAP70 (Homo sapiens)
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
phospho tyrosine ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Phosphorylation of ZAP-70 by Lck (Homo sapiens)
Antigen-bearing MHC Class II :TCR complex:CD4: Lck phosphorylated at Tyr394 [plasma membrane] (Homo sapiens)
T-cell receptor complex [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
phospho tyrosine ZAP-70 [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
Recruitment of ZAP-70 to phosphorylated ITAMs (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
ZAP-70 bound to phosphorylated ITAM motifs [plasma membrane] (Homo sapiens)
Antigen-bearing MHC Class II: TCR with phosphorylated ITAMs:CD4 [plasma membrane] (Homo sapiens)
T-cell receptor complex with phosphorylated ITAMs [plasma membrane] (Homo sapiens)
T-cell receptor [plasma membrane] (Homo sapiens)
TCR chain alpha [plasma membrane] (Homo sapiens)
General
In view of the highly variable nature of T-cell receptors, this biological object is an approximate and fragmented representation of a TCR, given the limitations of alpha and beta chain enumeration in UniProt.
Participants
members
TRAC [plasma membrane]
(Homo sapiens)
TCRA [plasma membrane]
(Homo sapiens)
T-cell receptor alpha chain V region PY14 precursor [plasma membrane]
(Homo sapiens)
TRAV19 [plasma membrane]
(Homo sapiens)
Participates
as a component of
T-cell receptor [plasma membrane] (Homo sapiens)
Inferred To
TCR chain alpha [plasma membrane]
(Bos taurus)
TCR chain alpha [plasma membrane]
(Canis familiaris)
TCR chain alpha [plasma membrane]
(Gallus gallus)
TCR chain alpha [plasma membrane]
(Mus musculus)
TCR chain alpha [plasma membrane]
(Rattus norvegicus)
TCR chain alpha [plasma membrane]
(Sus scrofa)
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