Active TRKA binds IRS1/2

Stable Identifier
R-HSA-198211
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytoplasmic side of plasma membrane
ReviewStatus
5/5
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Active TRKA binds IRS1/2
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
IRS1 and IRS2 bind directly to TRK receptors phosphorylated at Y490, through their phosphotyrosine- binding (PTB) domains.
Participants
Input
Output
Participates
as an event of
Inferred From
Active NTRK1 binds IRS1/2 (Mus musculus)
Authored
Nasi, S  (2006-10-10)
Annibali, D  (2006-10-10)
Reviewed
Greene, LA  (2007-11-08)
Created
Jassal, B  (2007-05-21)
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