TRKA phosphorylates IRS

Stable Identifier
R-HSA-198295
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytoplasmic side of plasma membrane
ReviewStatus
5/5
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TRKA phosphorylates IRS
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IRS1 and IRS2 are tyrosine phosphorylated at multiple YXXM motifs by the active TRKA kinase (Miranda et al.2001).
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Input
Output
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as an event of
Catalyst Activity

transmembrane receptor protein tyrosine kinase activity of Activated TrkA receptor:IRS1/2 [plasma membrane]

Physical Entity
Activated TrkA receptor:IRS1/2 [plasma membrane] (Homo sapiens)
Activity
transmembrane receptor protein tyrosine kinase activity (GO:0004714)
Inferred From
NTRK1 phosphorylates IRS (Mus musculus)
Authored
Nasi, S  (2006-10-10)
Annibali, D  (2006-10-10)
Reviewed
Greene, LA  (2007-11-08)
Created
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