AKT phosphorylates CREB1

Stable Identifier
R-HSA-199298
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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AKT phosphorylates CREB (cAMP response element-binding protein) at serine 133 and activates gene expression via a CREB-dependent mechanism, thus promoting cell survival.

Literature References
PubMed ID Title Journal Year
9829964 CREB is a regulatory target for the protein kinase Akt/PKB

Du, K, Montminy, M

J Biol Chem 1998
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Event Information
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Catalyst Activity

protein serine/threonine kinase activity of p-T,p-S-AKT [nucleoplasm]

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