Reactome | SLC19A2 [plasma membrane]

SLC19A2 [plasma membrane]

Stable Identifier

R-HSA-199636

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Solute carrier family19 member 2, THTR1, Thiamine transporter 1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O60779 SLC19A2

Gene Names

SLC19A2, THT1, TRMA

Chain

chain:1-497

Reference Genes

BioGPS Gene:10560 SLC19A2

COSMIC (genes):SLC19A2 SLC19A2

CTD Gene:10560 SLC19A2

dbSNP Gene:10560 SLC19A2

ENSEMBL:ENSG00000117479 SLC19A2

HGNC:10938 SLC19A2

KEGG:hsa:10560 SLC19A2

Monarch:10560 SLC19A2

NCBI Gene:10560 SLC19A2

OMIM:603941 SLC19A2

UCSC:O60779 SLC19A2

Reference Transcript

Other Identifiers

10560

11723148_a_at

11723149_a_at

11744616_a_at

16696177

209681_PM_at

209681_at

2443336

2443337

2443338

2443339

2443342

2443343

2443344

2443345

2443346

2443347

2443350

2443351

2443352

2443355

2443356

2443357

2443358

35248_at

7922162

A_23_P160466

GE55260

GO:0005215

GO:0005515

GO:0005886

GO:0006766

GO:0006790

GO:0007283

GO:0008517

GO:0009229

GO:0015234

GO:0015884

GO:0015888

GO:0016020

GO:0022414

GO:0031923

GO:0035461

GO:0042723

GO:0051180

GO:0055085

GO:0071934

GO:0090482

HMNXSV003005621

ILMN_2201668

PH_hs_0002598

TC01003497.hg

g5453325_3p_at

Participates

as a member of

SLC19A2/3 [plasma membrane] (Homo sapiens)

Inferred To

slc19a2 [plasma membrane] (Xenopus tropicalis)

folt-3 [plasma membrane] (Caenorhabditis elegans)

SLC19A2 [plasma membrane] (Bos taurus)

SLC19A2 [plasma membrane] (Canis familiaris)

SLC19A2 [plasma membrane] (Dictyostelium discoideum)

SLC19A2 [plasma membrane] (Gallus gallus)

SLC19A2 [plasma membrane] (Sus scrofa)

Slc19a2 [plasma membrane] (Mus musculus)

Slc19a2 [plasma membrane] (Rattus norvegicus)

Dmel\CG17036 [plasma membrane] (Drosophila melanogaster)

Cross References

Guide to Pharmacology - Targets

1015

ENSEMBL

ENST00000236137, ENSP00000236137, ENSG00000117479, ENST00000367804, ENSP00000356778

OpenTargets

ENSG00000117479

ZINC - Substances

S19A2_HUMAN

ZINC target

O60779

PRO

O60779

GlyGen

O60779

GeneCards

SLC19A2

HPA

ENSG00000117479-SLC19A2

Pharos - Targets

O60779

Orphanet

SLC19A2

ZINC - Predictions - Purchasable

S19A2_HUMAN

HMDB Protein

HMDBP02627

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P25090 FPR2	4	FPR2 [plasma membrane] (R-HSA-416408) FPR2 [tertiary granule membrane] (R-HSA-6803296) FPR2 [specific granule membrane] (R-HSA-6803319) FPR2 [ficolin-1-rich granule membrane] (R-HSA-6803335)	0.527	3
UniProt:P06576 ATP5F1B	6	ATP5F1B [mitochondrial matrix] (R-HSA-164576) ATP5B(1-47) [mitochondrial matrix] (R-HSA-8986172) ATP5B(1-529) [cytosol] (R-HSA-1267973) ATP5B(1-529) [mitochondrial intermembrane space] (R-HSA-1267985) ATP5B(1-529) [mitochondrial inner membrane] (R-HSA-1299440) ATP5B [mitochondrial inner membrane] (R-HSA-1299441)	0.527	2
UniProt:Q92911 SLC5A5	7	SLC5A5 T354P [plasma membrane] (R-HSA-5658154) SLC5A5 V59E [plasma membrane] (R-HSA-5658157) SLC5A5 G93R [plasma membrane] (R-HSA-5658172) SLC5A5 R124H [plasma membrane] (R-HSA-5658196) SLC5A5 C272* [plasma membrane] (R-HSA-5658167) SLC5A5 G395R [plasma membrane] (R-HSA-5658166) SLC5A5 [plasma membrane] (R-HSA-209833)	0.527	2
UniProt:P30556 AGTR1	2	AGTR1 [plasma membrane] (R-HSA-374247) AGTR1 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869071)	0.527	2
UniProt:P26842 CD27	1	CD27 [plasma membrane] (R-HSA-5666994)	0.527	2
UniProt:P80370 DLK1	1	DLK1 [plasma membrane] (R-HSA-1604447)	0.527	2
UniProt:P47900 P2RY1	1	P2RY1 [plasma membrane] (R-HSA-391956)	0.527	3
UniProt:P30825 SLC7A1	1	SLC7A1 [plasma membrane] (R-HSA-375771)	0.527	2
UniProt:Q9H5K3 POMK	1	POMK [endoplasmic reticulum membrane] (R-HSA-8879120)	0.527	2
UniProt:Q16581 C3AR1	3	C3AR1 [plasma membrane] (R-HSA-444727) C3AR1 [specific granule membrane] (R-HSA-6799516) C3AR1 [azurophil granule membrane] (R-HSA-6799517)	0.527	2

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