Reactome | p-S15,S356-RPS6KB2 [nucleoplasm]

p-S15,S356-RPS6KB2 [nucleoplasm]

Stable Identifier

R-HSA-199844

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

p-S15,356-RPS6KB2, Phospho-Ribosomal protein S6 kinase 2, K6B2_HUMAN, RPS6KB2

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External Reference Information

External Reference

UniProt:Q9UBS0 RPS6KB2

Gene Names

RPS6KB2, STK14B

Chain

chain:1-482

Reference Genes

BioGPS Gene:6199 RPS6KB2

COSMIC (genes):RPS6KB2 RPS6KB2

CTD Gene:6199 RPS6KB2

dbSNP Gene:6199 RPS6KB2

ENSEMBL:ENSG00000175634 RPS6KB2

HGNC:10437 RPS6KB2

KEGG:hsa:6199 RPS6KB2

Monarch:6199 RPS6KB2

NCBI Entrez Gene:6199 RPS6KB2

OMIM:608939 RPS6KB2

UCSC:Q9UBS0 RPS6KB2

Reference Transcript

RefSeq:NM_003952.3 RPS6KB2

Other Identifiers

11742837_x_at

11747560_a_at

11747561_s_at

11760951_x_at

16727861

203777_PM_s_at

203777_s_at

3337068

3337069

3337070

3337071

3337072

3337073

3337074

3337075

3337076

3337077

3337078

3337079

3337080

3337081

3337082

3337083

3337084

3337085

3337086

3337087

3337088

3337089

3337090

3337091

3337092

3337093

3337094

3337095

3337096

3337097

3337098

3337099

3337100

3337101

41374_at

6199

7941900

A_14_P114012

A_14_P114204

A_23_P24318

A_33_P3230488

GE53423

GO:0000166

GO:0002181

GO:0003824

GO:0004672

GO:0004674

GO:0004711

GO:0005524

GO:0005634

GO:0005654

GO:0005737

GO:0006412

GO:0006468

GO:0007165

GO:0016301

GO:0016740

GO:0031929

GO:0038202

GO:0042277

GO:0045948

GO:0046627

GO:0106310

GO:0140096

HMNXSV003026054

ILMN_1761175

ILMN_2364357

PH_hs_0027748

TC11000691.hg

g4506738_3p_s_at

Participates

as an output of

Other forms of this molecule

RPS6KB2 [nucleoplasm]

Inferred To

phospho-p-S15,S356-RPS6KB2 [nucleoplasm] (Bos taurus)

phospho-p-S15,S356-RPS6KB2 [nucleoplasm] (Caenorhabditis elegans)

phospho-p-S15,S356-RPS6KB2 [nucleoplasm] (Canis familiaris)

phospho-p-S15,S356-RPS6KB2 [nucleoplasm] (Dictyostelium discoideum)

phospho-p-S15,S356-RPS6KB2 [nucleoplasm] (Drosophila melanogaster)

phospho-p-S15,S356-RPS6KB2 [nucleoplasm] (Gallus gallus)

phospho-p-S15,S356-RPS6KB2 [nucleoplasm] (Mus musculus)

phospho-p-S15,S356-RPS6KB2 [nucleoplasm] (Rattus norvegicus)

phospho-p-S15,S356-RPS6KB2 [nucleoplasm] (Saccharomyces cerevisiae)

phospho-p-S15,S356-RPS6KB2 [nucleoplasm] (Schizosaccharomyces pombe)

phospho-p-S15,S356-RPS6KB2 [nucleoplasm] (Sus scrofa)

Homologues of p-S15,S356-RPS6KB2 [nucleoplasm] (Caenorhabditis elegans)

Homologues of p-S15,S356-RPS6KB2 [nucleoplasm] (Drosophila melanogaster)

Modified Residues

Name

O-phospho-L-serine at 15

Coordinate

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at 356

Coordinate

356

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

NP_003943.2

Guide to Pharmacology - Targets

1526

ENSEMBL

ENSP00000432847, ENSP00000308413, ENST00000312629, ENST00000528964, ENSG00000175634

OpenTargets

ENSG00000175634

GeneCards

RPS6KB2

HPA

ENSG00000175634-RPS6KB2

ZINC - Substances

KS6B2_HUMAN

ZINC target

Q9UBS0

PRO

Q9UBS0

Pharos - Targets

Q9UBS0

ZINC - Predictions - Purchasable

KS6B2_HUMAN

HMDB Protein

HMDBP11579

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P67870 CSNK2B	5	CSNK2B [cytosol] (R-HSA-201693) CSNK2B [nucleoplasm] (R-HSA-6805067) CSNK2B [secretory granule lumen] (R-HSA-6801319) CSNK2B [extracellular region] (R-HSA-6806508) CSNK2B [ficolin-1-rich granule lumen] (R-HSA-6801290)	0.589	3