RSK1/2/3 phosphorylates CREB at Serine 119

Stable Identifier
R-HSA-199895
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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RSK1/2/3 phosphorylates CREB at Serine 119
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CREB is phosphorylated at S133 by RSK1/2/3.
Literature References
PubMed ID Title Journal Year
9770464 Rsk-2 activity is necessary for epidermal growth factor-induced phosphorylation of CREB protein and transcription of c-fos gene

Jacquot, S, Hanauer, A, De Cesare, D, Sassone-Corsi, P

Proc Natl Acad Sci U S A 1998
Participants
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Output
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as an event of
Catalyst Activity

protein serine/threonine kinase activity of Phospho-Ribosomal protein S6 kinase [nucleoplasm]

Physical Entity
Phospho-Ribosomal protein S6 kinase [nucleoplasm] (Homo sapiens)
Activity
protein serine/threonine kinase activity (GO:0004674)
Orthologous Events
RSK1/2/3 phosphorylates CREB at Serine 119 (Bos taurus)
RSK1/2/3 phosphorylates CREB at Serine 119 (Caenorhabditis elegans)
RSK1/2/3 phosphorylates CREB at Serine 119 (Canis familiaris)
RSK1/2/3 phosphorylates CREB at Serine 119 (Drosophila melanogaster)
RSK1/2/3 phosphorylates CREB at Serine 119 (Gallus gallus)
RSK1/2/3 phosphorylates CREB at Serine 119 (Mus musculus)
RSK1/2/3 phosphorylates CREB at Serine 119 (Rattus norvegicus)
RSK1/2/3 phosphorylates CREB at Serine 119 (Sus scrofa)
RSK1/2/3 phosphorylates CREB at Serine 119 (Xenopus tropicalis)
Authored
Nasi, S  (2006-10-10)
Annibali, D  (2006-10-10)
Reviewed
Greene, LA  (2007-11-08)
Created
Jassal, B  (2007-07-13)
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