Reactome | PCOLCE [extracellular region]

PCOLCE [extracellular region]

Stable Identifier

R-HSA-2002444

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

PCPE1, Procollagen C-endopeptidase enhancer 1, PCOC1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q15113 PCOLCE

Gene Names

PCOLCE, PCPE1

Chain

signal peptide:1-25, chain:26-449

Reference Genes

BioGPS Gene:5118 PCOLCE

COSMIC (genes):PCOLCE PCOLCE

CTD Gene:5118 PCOLCE

dbSNP Gene:5118 PCOLCE

ENSEMBL:ENSG00000106333 PCOLCE

HGNC:8738 PCOLCE

KEGG:hsa:5118 PCOLCE

Monarch:5118 PCOLCE

NCBI Gene:5118 PCOLCE

OMIM:600270 PCOLCE

UCSC:Q15113 PCOLCE

Reference Transcript

RefSeq:NM_002593.3 PCOLCE

Other Identifiers

11715652_a_at

11761772_at

11761773_x_at

17049408

202465_PM_at

202465_at

3015683

3015684

3015685

3015686

3015687

3015688

3015689

3015690

3015691

3015692

3015693

3015694

3015695

3015696

3015697

3015698

3015699

3015700

3015701

3015702

3015703

31609_s_at

5118

8134869

A_14_P121217

A_23_P251499

GE62586

GO:0005198

GO:0005201

GO:0005515

GO:0005518

GO:0005576

GO:0005615

GO:0006508

GO:0008201

GO:0016504

GO:0030312

GO:0031012

GO:0032964

GO:0043226

GO:0062023

GO:0070062

GO:0098772

HMNXSV003017153

L33799_at

PH_hs_0011876

TC07000627.hg

g7262388_3p_at

Participates

as a member of

PCOLCEs [extracellular region] (Homo sapiens)

as a component of

TLL2:PCPE1 [extracellular region] (Homo sapiens)

Inferred To

Pcolce [extracellular region] (Mus musculus)

Pcolce [extracellular region] (Rattus norvegicus)

pcolceb [extracellular region] (Danio rerio)

PCOLCE [extracellular region] (Bos taurus)

PCOLCE [extracellular region] (Caenorhabditis elegans)

PCOLCE [extracellular region] (Canis familiaris)

PCOLCE [extracellular region] (Sus scrofa)

Cross References

ENSEMBL

ENST00000223061, ENSP00000223061, ENSG00000106333

OpenTargets

ENSG00000106333

GeneCards

PCOLCE

HPA

ENSG00000106333-PCOLCE

PRO

Q15113

Pharos - Targets

Q15113

PDB

6FZV, 9EN2, 1UAP, 6FZW

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P43407 Sdc2	20	Sdc2 [plasma membrane] (R-MMU-2090052) Sdc2 [plasma membrane] (R-MMU-2076683) Sdc2 [plasma membrane] (R-MMU-2076661) Sdc2 [plasma membrane] (R-MMU-2076644) Sdc2 [plasma membrane] (R-MMU-2076643) Sdc2 [plasma membrane] (R-MMU-2076631) Sdc2 [plasma membrane] (R-MMU-2076665) Sdc2 [endoplasmic reticulum lumen] (R-MMU-8956741) phospho-Sdc2 [endoplasmic reticulum lumen] (R-MMU-8956945) Sdc2 [Golgi lumen] (R-MMU-2054101) Sdc2 [Golgi lumen] (R-MMU-2064109) Sdc2 [Golgi lumen] (R-MMU-2064132) Sdc2 [Golgi lumen] (R-MMU-2063988) Sdc2 [Golgi lumen] (R-MMU-2063997) Sdc2 [Golgi lumen] (R-MMU-2076603) Sdc2 [Golgi lumen] (R-MMU-2076443) Sdc2 [Golgi lumen] (R-MMU-2076607) Sdc2 [Golgi lumen] (R-MMU-2076576) Sdc2 [Golgi lumen] (R-MMU-2076361) Sdc2 [Golgi lumen] (R-MMU-2076397)	0.576	4
UniProt:P07996 THBS1	5	THBS1 [platelet alpha granule lumen] (R-HSA-114701) THBS1 [extracellular region] (R-HSA-66518) O-fuc-THBS1 [endoplasmic reticulum lumen] (R-HSA-5173278) glc-fuc-THBS1 [endoplasmic reticulum lumen] (R-HSA-5172997) THBS1 [endoplasmic reticulum lumen] (R-HSA-5173263)	0.558	3
UniProt:P18828 Sdc1	20	Sdc1 [plasma membrane] (R-MMU-2076693) Sdc1 [plasma membrane] (R-MMU-2076652) Sdc1 [plasma membrane] (R-MMU-2076666) Sdc1 [plasma membrane] (R-MMU-2076672) Sdc1 [plasma membrane] (R-MMU-2076691) Sdc1 [plasma membrane] (R-MMU-2076626) Sdc1 [plasma membrane] (R-MMU-174758) Sdc1 [Golgi lumen] (R-MMU-2054105) Sdc1 [Golgi lumen] (R-MMU-2064146) Sdc1 [Golgi lumen] (R-MMU-2064148) Sdc1 [Golgi lumen] (R-MMU-2064247) Sdc1 [Golgi lumen] (R-MMU-2064082) Sdc1 [Golgi lumen] (R-MMU-2076309) Sdc1 [Golgi lumen] (R-MMU-2076444) Sdc1 [Golgi lumen] (R-MMU-2076321) Sdc1 [Golgi lumen] (R-MMU-2076339) Sdc1 [Golgi lumen] (R-MMU-2076314) Sdc1 [Golgi lumen] (R-MMU-2076558) Sdc1 [Golgi lumen] (R-MMU-2076349) Sdc1 [Golgi lumen] (R-MMU-2076561)	0.499	4

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