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NMNAT1 [nucleoplasm]
Stable Identifier
R-HSA-200484
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Nicotinamide mononucleotide adenylyltransferase 1
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Nicotinate metabolism (Homo sapiens)
NMNAT1 transfers an adenylyl group from ATP to NAMN to yield NAAD (Homo sapiens)
6xNMNAT1:6xZn2+ [nucleoplasm] (Homo sapiens)
NMNAT1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9HAN9 NMNAT1
Gene Names
NMNAT1, NMNAT
Chain
chain:1-279
Reference Genes
BioGPS Gene:64802 NMNAT1
COSMIC (genes):NMNAT1 NMNAT1
CTD Gene:64802 NMNAT1
dbSNP Gene:64802 NMNAT1
ENSEMBL:ENSG00000173614 NMNAT1
HGNC:17877 NMNAT1
KEGG:hsa:64802 NMNAT1
Monarch:64802 NMNAT1
NCBI Gene:64802 NMNAT1
OMIM:608700 NMNAT1
UCSC:Q9HAN9 NMNAT1
Reference Transcript
RefSeq:NM_001297778.1 NMNAT1
RefSeq:NM_022787.3 NMNAT1
RefSeq:XM_017002107.1 NMNAT1
Other Identifiers
11729312_at
11758501_s_at
1569631_PM_at
1569631_at
16658736
223692_PM_at
223692_at
229852_PM_at
229852_at
2319519
2319520
2319523
2319524
2319525
2319526
2319527
2319528
2319529
2319530
2319531
2319532
2319533
2319534
2319535
2319536
2319537
51857_at
54414_at
64802
7897509
81367_at
A_24_P139742
A_33_P3215193
GE82727
GE88034
GE88035
GO:0000309
GO:0000785
GO:0003824
GO:0004515
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0006355
GO:0009058
GO:0009165
GO:0009435
GO:0009611
GO:0016604
GO:0016740
GO:0016779
GO:0019363
GO:0042802
GO:0043226
GO:0043410
GO:0043524
GO:0045892
GO:0055086
GO:0060090
GO:0070566
GO:0140768
GO:1901135
GO:1902511
GO:1990966
HMNXSV003012168
HMNXSV003050052
Hs.58251.0.A1_3p_at
Hs2.434236.1.S1_3p_at
ILMN_1692413
PH_hs_0031265
TC01000122.hg
Participates
as a component of
6xNMNAT1:6xZn2+ [nucleoplasm] (Homo sapiens)
Inferred To
NMNAT1 [nucleoplasm]
(Bos taurus)
NMNAT1 [nucleoplasm]
(Caenorhabditis elegans)
NMNAT1 [nucleoplasm]
(Canis familiaris)
NMNAT1 [nucleoplasm]
(Dictyostelium discoideum)
NMNAT1 [nucleoplasm]
(Gallus gallus)
NMNAT1 [nucleoplasm]
(Mus musculus)
NMNAT1 [nucleoplasm]
(Saccharomyces cerevisiae)
NMNAT1 [nucleoplasm]
(Schizosaccharomyces pombe)
NMNAT1 [nucleoplasm]
(Sus scrofa)
Nmnat1 [nucleoplasm]
(Rattus norvegicus)
nmnat1 [nucleoplasm]
(Danio rerio)
Nmnat [nucleoplasm]
(Drosophila melanogaster)
Cross References
ENSEMBL
ENST00000462686
,
ENST00000377205
,
ENSP00000435134
,
ENSP00000366410
OpenTargets
ENSG00000173614
HPA
ENSG00000173614-NMNAT1
PRO
Q9HAN9
Pharos - Targets
Q9HAN9
GlyGen
Q9HAN9
Orphanet
NMNAT1
HMDB Protein
HMDBP00335
PDB
1KKU
,
1GZU
,
1KR2
,
1KQO
,
8QE8
,
1KQN
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P52292 KPNA2
2
KPNA2 [cytosol]
(R-HSA-205976)
KPNA2 [nucleoplasm]
(R-HSA-206045)
0.781
8
UniProt:P24863 CCNC
1
CCNC [nucleoplasm]
(R-HSA-212418)
0.666
4
UniProt:Q96EB6 SIRT1
1
SIRT1 [nucleoplasm]
(R-HSA-427531)
0.591
3
UniProt:P52294 KPNA1
2
KPNA1 [cytosol]
(R-HSA-180612)
KPNA1 [nucleoplasm]
(R-HSA-188865)
0.556
3
UniProt:Q9NRD5 PICK1
2
PICK1 [plasma membrane]
(R-HSA-416989)
PICK1 [endocytic vesicle membrane]
(R-HSA-417017)
0.556
3
UniProt:O43159 RRP8
1
RRP8 [nucleoplasm]
(R-HSA-427524)
0.527
3
UniProt:P62753 RPS6
4
RPS6 [cytosol]
(R-HSA-72381)
p-5S-RPS6 [cytosol]
(R-HSA-165727)
3OHR147-RPS6 [cytosol]
(R-HSA-9629876)
RPS6 [nucleoplasm]
(R-HSA-6790606)
0.483
2
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