Reactome | BAG6 [cytosol]

BAG6 [cytosol]

Stable Identifier

R-HSA-201567

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

BAT3

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P46379 BAG6

Gene Names

BAG6, BAT3, G3

Chain

chain:1-1132

Reference Genes

BioGPS Gene:7917 BAG6

COSMIC (genes):BAG6 BAG6

CTD Gene:7917 BAG6

dbSNP Gene:7917 BAG6

ENSEMBL:ENSG00000204463 BAG6

HGNC:13919 BAG6

KEGG:hsa:7917 BAG6

Monarch:7917 BAG6

NCBI Gene:7917 BAG6

OMIM:142590 BAG6

UCSC:P46379 BAG6

Reference Transcript

Participates

as a component of

BAG6:GET4:UBL4A [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000204463

ENSEMBL

ENST00000552605, ENSP00000446525, ENSG00000204463, ENSG00000229524, ENSG00000227761, ENST00000439687, ENSP00000354875, ENSP00000482413, ENSP00000402856, ENST00000551350, ENST00000362049, ENST00000383448, ENST00000451932, ENST00000615725, ENST00000443182, ENST00000613474, ENSP00000477951, ENSP00000447546, ENSP00000447946, ENSG00000228760, ENSP00000479238, ENST00000552116, ENSP00000502941, ENSP00000211379, ENSP00000397894, ENSP00000390966, ENSP00000372938, ENSG00000096155, ENSG00000234651, ENST00000449450, ENST00000211379, ENSP00000389121, ENSP00000477867, ENSP00000365143, ENSP00000484238, ENSP00000410156, ENST00000375976, ENST00000615143, ENST00000615224, ENST00000442479, ENST00000361076, ENST00000419847, ENST00000383446, ENST00000621056, ENSP00000412110, ENSP00000478966, ENSP00000354368, ENSP00000413698, ENST00000676615, ENSP00000372940, ENSG00000233348, ENST00000417144, ENST00000617635

GeneCards

BAG6

HPA

ENSG00000204463-BAG6

PRO

P46379

Pharos - Targets

P46379

GlyGen

P46379

PDB

7RU9, 7RUA, 2N9P, 4WWR, 4DWF, 6AU8, 1WX9, 7RUC, 4X86, 4EEW

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P11802 CDK4	3	p-T172-CDK4 [nucleoplasm] (R-HSA-113830) CDK4 [nucleoplasm] (R-HSA-113843) CDK4 [cytosol] (R-HSA-68330)	0.573	2
UniProt:Q7Z434 MAVS	2	MAVS [mitochondrial outer membrane] (R-HSA-913730) K48polyUb-MAVS [mitochondrial outer membrane] (R-HSA-983463)	0.499	2
UniProt:P13569 CFTR	17	misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) CFTR [plasma membrane] (R-HSA-383188) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR G542* [plasma membrane] (R-HSA-5678986) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) ub-CFTR F508del [cytosol] (R-HSA-8866838) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR [endosome membrane] (R-HSA-6782965) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [lysosomal membrane] (R-HSA-5627279) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104)	0.483	8

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