Reactome | VIM [cytosol]

VIM [cytosol]

Stable Identifier

R-HSA-201600

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

vimentin (2-466 fragment)

Locations in the PathwayBrowser for interactor UniProt:Q99619 SPSB2

Expand all

External Reference Information

External Reference

UniProt:P08670 VIM

Gene Names

VIM

Chain

initiator methionine:, chain:2-466

Reference Genes

BioGPS Gene:7431 VIM

COSMIC (genes):VIM VIM

CTD Gene:7431 VIM

dbSNP Gene:7431 VIM

ENSEMBL:ENSG00000026025 VIM

ENSEMBL_homo_sapiens_GENE:ENSG00000026025.16 VIM

HGNC:12692 VIM

KEGG Gene (Homo sapiens):7431 VIM

Monarch:7431 VIM

NCBI Gene:7431 VIM

OMIM:193060 VIM

Reference Transcript

Other Identifiers

11731394_a_at

11755943_x_at

16702767

201426_PM_s_at

201426_s_at

3236965

3236966

3236967

3236968

3236970

3236971

3236972

3236973

3236974

3236975

3236976

3236977

3236978

3236980

3236987

3236988

3236991

3236993

3236995

3236997

3236999

3237000

3237001

3237002

3237003

3237004

34091_s_at

7431

75309_at

7926368

A_23_P161190

A_23_P161194

GE81272

GO:0002376

GO:0003723

GO:0003725

GO:0005198

GO:0005200

GO:0005212

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005737

GO:0005777

GO:0005815

GO:0005829

GO:0005856

GO:0005882

GO:0005886

GO:0005925

GO:0007010

GO:0010628

GO:0010977

GO:0014002

GO:0016020

GO:0016071

GO:0016363

GO:0019904

GO:0030154

GO:0030424

GO:0031175

GO:0031252

GO:0031410

GO:0032967

GO:0042802

GO:0042995

GO:0043005

GO:0043226

GO:0043488

GO:0045103

GO:0045109

GO:0045111

GO:0045335

GO:0048856

GO:0060020

GO:0060090

GO:0070062

GO:0070307

GO:0071222

GO:0071225

GO:0071346

GO:0097110

GO:0098542

GO:1990254

HMNXSV003038196

Hs.297753.0.A1_3p_a_at

ILMN_1782538

ILMN_2058251

PH_hs_0025444

TC10000126.hg

Z19554_s_at

Participates

as a candidate of

RHOBTB1 interacting proteins [cytosol] (Homo sapiens)

as a component of

Z Disk Complex [cytosol] (Homo sapiens)

as a member of

STAT3-upregulated cytosolic proteins [cytosol] (Homo sapiens)

as an input of

Other forms of this molecule

VIM(2-85) [cytosol]

VIM(86-466) [cytosol]

VIM(430-466) [cytosol]

VIM(2-429) [cytosol]

VIM(260-466) [cytosol]

VIM(2-259) [cytosol]

Vimentin [late endosome lumen]

Vimentin [microtubule organizing center]

Vimentin [cytosol]

Vimentin [lysosomal lumen]

Inferred To

VIM [cytosol] (Bos taurus)

VIM [cytosol] (Canis familiaris)

VIM [cytosol] (Gallus gallus)

VIM [cytosol] (Sus scrofa)

viml [cytosol] (Danio rerio)

vim [cytosol] (Xenopus tropicalis)

Vim [cytosol] (Mus musculus)

Vim [cytosol] (Rattus norvegicus)

Cross References

RefSeq

XP_006717563.1, NP_003371.2

OpenTargets

ENSG00000026025

GeneCards

P08670

HPA

ENSG00000026025-VIM

Ensembl

ENST00000544301, ENST00000224237, ENSP00000224237, ENSG00000026025, ENSP00000446007

PRO

P08670

Pharos - Targets

P08670

Orphanet

19232

HMDB Protein

HMDBP01682

PDB

3S4R, 6YXK, 1GK6, 4MDJ, 6BIR, 6ATI, 4MD5, 4YPC, 4MCZ, 6ATF, 3KLT, 1GK4, 4MDI, 3TRT, 4MCY, 4YV3, 5WHF, 4MD0, 3G1E, 3UF1, 8RVE, 3SWK, 1GK7, 3SSU

Interactors (128)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P08670 VIM	11	VIM(2-85) [cytosol] (R-HSA-350264) VIM(86-466) [cytosol] (R-HSA-350294) VIM(430-466) [cytosol] (R-HSA-350316) VIM(2-429) [cytosol] (R-HSA-350317) VIM(260-466) [cytosol] (R-HSA-350314) VIM(2-259) [cytosol] (R-HSA-350323) VIM [cytosol] (R-HSA-201600) Vimentin [late endosome lumen] (R-HSA-9660019) Vimentin [microtubule organizing center] (R-HSA-9657898) Vimentin [cytosol] (R-HSA-9646687) Vimentin [lysosomal lumen] (R-HSA-9659977)	0.907	11
UniProt:P07197 NFM			0.88	9
UniProt:P07196 NEFL	1	NEFL [cytosol] (R-HSA-432284)	0.844	6
UniProt:P14136 GFAP	3	p-GFAP [lysosomal membrane] (R-HSA-9626054) GFAP [lysosomal membrane] (R-HSA-9625195) GFAP [cytosol] (R-HSA-1253311)	0.831	10
UniProt:P35900 KRT20	1	KRT20 [cytosol] (R-HSA-6809603)	0.83	8
UniProt:P17661 DES	1	DES [cytosol] (R-HSA-390570)	0.818	8
UniProt:P48681 NEST			0.802	5
UniProt:Q9HC29 NOD2	1	NOD2 [cytosol] (R-HSA-168411)	0.79	8
UniProt:O95251 KAT7	1	KAT7 [nucleoplasm] (R-HSA-3321823)	0.747	4
UniProt:Q9H7C4 SYNCI			0.742	7
UniProt:Q8N3L3 TXLNB			0.718	6
UniProt:Q96PV4 PNMA5			0.718	6
UniProt:P31749 AKT1	14	p-T308,S473-AKT1 E17K [nucleoplasm] (R-HSA-2399994) p-T308,S473-AKT1 E17K [cytosol] (R-HSA-2243935) AKT1 E17K [cytosol] (R-HSA-2219526) p-S473-AKT1 E17K [plasma membrane] (R-HSA-2243944) AKT1 E17K [plasma membrane] (R-HSA-1500573) p-S473-AKT1 [cytosol] (R-HSA-9841264) p-T308,S473-AKT1 [plasma membrane] (R-HSA-199430) p-Y315,Y326-AKT1 [cytosol] (R-HSA-8848757) p-T308-AKT1 [cytosol] (R-HSA-198634) AKT1 [cytosol] (R-HSA-58252) AKT1 [plasma membrane] (R-HSA-199416) p-S473-AKT1 [plasma membrane] (R-HSA-377265) p-T308,S473-AKT1 [cytosol] (R-HSA-198356) p-T308,S473-AKT1 [nucleoplasm] (R-HSA-198357)	0.706	29
UniProt:P63104 YWHAZ	2	YWHAZ [nucleoplasm] (R-HSA-450469) YWHAZ [cytosol] (R-HSA-206099)	0.669	3
UniProt:Q6ZU52 K0408			0.666	4
UniProt:P41219 PERI			0.666	4
UniProt:Q12824 SMARCB1	1	SMARCB1 [nucleoplasm] (R-HSA-389261)	0.666	4
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.666	4
UniProt:P0DTD1-PRO_0000449633 REP			0.666	4
UniProt:P61981 YWHAG	1	YWHAG [cytosol] (R-HSA-380312)	0.65	3
UniProt:Q16352 AINX			0.643	3
UniProt:P58107 EPIPL			0.643	3
UniProt:Q9NQH7 XPP3			0.638	3
UniProt:P14340-PRO_0000037966			0.636	10
UniProt:Q14194 CRMP1	4	p-Y-CRMP1 [cytosol] (R-HSA-399784) CRMP1 [cytosol] (R-HSA-398120) p-T509,T514,S518,S522-CRMP1 [cytosol] (R-HSA-399777) p-S522-CRMP1 [cytosol] (R-HSA-399779)	0.635	3
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.615	11
UniProt:O76036 NCR1	1	NCR1 [plasma membrane] (R-HSA-197739)	0.611	3
UniProt:Q9Y4K0 LOXL2	3	LOXL2(26-?) [extracellular region] (R-HSA-2022106) LOXL2 [extracellular region] (R-HSA-2022142) LOXL2(?-774) [extracellular region] (R-HSA-2022136)	0.602	6
UniProt:P83110-2 HTRA3			0.599	5
UniProt:Q9BYF1 ACE2	5	ACE2(18-805) [plasma membrane] (R-HSA-2022344) ACE2 [endoplasmic reticulum lumen] (R-HSA-9683474) glycosylated-ACE2 [endocytic vesicle membrane] (R-HSA-9686721) ACE2 [endocytic vesicle membrane] (R-HSA-9698958) glycosylated-ACE2 [plasma membrane] (R-HSA-9683480)	0.599	4
UniProt:Q13835-2 PKP1			0.591	3
UniProt:P27958-PRO_0000037566			0.584	4
UniProt:P83110-1 HTRA3			0.577	4
UniProt:P05787 KRT8	1	KRT8 [cytosol] (R-HSA-446043)	0.564	2
UniProt:Q8TCE9 PPL13			0.556	3
IntAct:EBI-25881637 CCSB			0.556	3
UniProt:Q15560 TCEA2			0.556	3
UniProt:O15273 TCAP	1	TCAP [cytosol] (R-HSA-390571)	0.556	3
UniProt:Q9HAQ2 KIF9	1	KIF9 [cytosol] (R-HSA-984616)	0.556	3
UniProt:Q8IVT4 Q8IVT4			0.556	3
UniProt:Q9UJD0 RIMS3			0.556	3
IntAct:EBI-25881483 CCSB			0.556	3
UniProt:Q6IAA8 LAMTOR1	5	LAMTOR1 [specific granule membrane] (R-HSA-6799631) LAMTOR1 [lysosomal membrane] (R-HSA-5653582) LAMTOR1 [azurophil granule membrane] (R-HSA-6799633) LAMTOR1 [plasma membrane] (R-HSA-6806270) LAMTOR1 [ficolin-1-rich granule membrane] (R-HSA-6801003)	0.556	3
UniProt:Q13895 BYSL	2	BYSL [nucleoplasm] (R-HSA-6791526) BYSL [cytosol] (R-HSA-6791518)	0.556	3
UniProt:Q8NI38 IKBD			0.556	3
UniProt:Q8TAB5 CA216			0.556	3
UniProt:Q6ZQX7-4 Q6ZQX74			0.556	3
UniProt:Q8WUY3 PRUN2			0.556	3
UniProt:Q9Y3D0 CIAO2B	1	FAM96B [cytosol] (R-HSA-2161124)	0.556	3
UniProt:Q9H6U6 BCAS3			0.556	3
UniProt:Q7Z3I7 ZN572			0.556	3
UniProt:Q6NXG1 ESRP1	3	ESRP1 [nucleoplasm] (R-HSA-6803472) ESRP1(1-606)-p-RAF1(227-648) fusion [cytosol] (R-HSA-6802523) ESRP1(1-606)-RAF1(227-648) fusion [cytosol] (R-HSA-6802312)	0.556	3
UniProt:Q9H6L4 ARMC7			0.556	3
UniProt:Q08117-2 TLE5			0.556	3
UniProt:Q9HC52 CBX8	1	CBX8 [nucleoplasm] (R-HSA-389117)	0.556	3
UniProt:Q6DHV7-2 Q6DHV72			0.556	3
UniProt:Q9BWG6 SCNM1			0.556	3
UniProt:Q6NYC8 PPR18			0.556	3
UniProt:Q14847-2 LASP1			0.556	3
UniProt:Q9UBB4 ATX10			0.556	3
UniProt:B7ZLI8 B7ZLI8			0.556	3
UniProt:O60506-4 SYNCRIP			0.556	3
UniProt:Q96HB5 CC120			0.556	3
UniProt:P55040 GEM	1	GEM [plasma membrane] (R-HSA-9769962)	0.556	3
UniProt:Q9NS73-5 MBIP			0.556	3
UniProt:Q4G1C9-2 Q4G1C92			0.556	3
UniProt:Q7Z403 TMC6	3	TMC6 [tertiary granule membrane] (R-HSA-6800920) TMC6 [plasma membrane] (R-HSA-6800446) TMC6 [specific granule membrane] (R-HSA-6799712)	0.556	3
UniProt:I6L9F6 I6L9F6			0.556	3
UniProt:Q7Z614-3 SNX20			0.556	3
UniProt:O95678 KRT75	1	KRT75 [cytosol] (R-HSA-6809652)	0.556	3
UniProt:Q16512 PKN1	3	p-T774-PKN1 [nucleoplasm] (R-HSA-5625721) p-T774-PKN1 [cytosol] (R-HSA-5623651) PKN1 [cytosol] (R-HSA-5623613)	0.556	3
UniProt:O60437 PPL	2	PPL [cytosol] (R-HSA-6810850) PPL [cornified envelope] (R-HSA-8847709)	0.556	3
UniProt:Q3B820 F161A			0.556	3
UniProt:Q96BD6 SPSB1	1	SPSB1 [cytosol] (R-HSA-976024)	0.556	3
UniProt:Q2TBE0 CWF19L2	1	CWF19L2 [nucleoplasm] (R-HSA-9770846)	0.556	3
IntAct:EBI-25861394 CCSB			0.556	3
UniProt:Q12888 TP53BP1	3	monoSUMO1-K-TP53BP1 [nucleoplasm] (R-HSA-2997591) p-S25,S1778-TP53BP1 [nucleoplasm] (R-HSA-5683418) TP53BP1 [nucleoplasm] (R-HSA-61175)	0.556	3
UniProt:P17024 ZNF20	1	ZNF20 [nucleoplasm] (R-HSA-975024)	0.556	3
UniProt:Q9H270 VPS11	1	VPS11 [endosome membrane] (R-HSA-2197802)	0.556	3
UniProt:Q08AM6 VAC14	3	VAC14 [Golgi membrane] (R-HSA-1806235) VAC14 [early endosome membrane] (R-HSA-1806207) VAC14 [late endosome membrane] (R-HSA-1806219)	0.556	3
UniProt:Q8N302-2 Q8N3022			0.556	3
UniProt:Q96LI6 HSFY1			0.556	3
UniProt:P12757 SKIL	1	SKIL [nucleoplasm] (R-HSA-2186596)	0.556	3
UniProt:Q8WUE5 CT55			0.556	3
UniProt:Q96GL9 F163A			0.556	3
UniProt:P54819 AK2	1	AK2 [mitochondrial intermembrane space] (R-HSA-57822)	0.556	3
UniProt:O77932 DXO			0.556	3
UniProt:O15287 FANCG	2	FANCG [nucleoplasm] (R-HSA-419532) FANCG [cytosol] (R-HSA-420788)	0.556	3
UniProt:Q5VYS8-5 TUT7			0.556	3
UniProt:Q5T1C6 THEM4	3	THEM4 [mitochondrial matrix] (R-HSA-162408) THEM4 [cytosol] (R-HSA-6809345) THEM4 [plasma membrane] (R-HSA-199437)	0.556	3
UniProt:Q99619 SPSB2	1	SPSB2 [cytosol] (R-HSA-976048)	0.556	3
UniProt:Q92551 IP6K1	2	IP6K1 [cytosol] (R-HSA-1604591) IP6K1 [nucleoplasm] (R-HSA-2023952)	0.556	3
UniProt:Q6XD76 ASCL4			0.556	3
UniProt:Q14142 TRIM14	1	TRIM14 [cytosol] (R-HSA-5624345)	0.556	3
UniProt:P15923-3 TCF3			0.556	3
UniProt:Q9UQM7 CAMK2A	6	p-T286-CAMK2A [plasma membrane] (R-HSA-432796) p-T286-CAMK2A [nucleoplasm] (R-HSA-444797) p-T286-CAMK2A [endocytic vesicle membrane] (R-HSA-416999) p-T286,T305,T306-CAMK2A [cytosol] (R-HSA-4332334) CAMK2A [cytosol] (R-HSA-4332329) p-T286-CAMK2A [cytosol] (R-HSA-445368)	0.556	3
UniProt:Q13428-5 TCOF1			0.556	3
UniProt:Q0VD86 INCA1			0.556	3
UniProt:Q9BVG8-5 KIFC3			0.556	3
UniProt:P26651 ZFP36	2	p-S60,S186-ZFP36 [cytosol] (R-HSA-450496) ZFP36 [cytosol] (R-HSA-450562)	0.556	3
UniProt:Q9BQE3 TUBA1C	9	AcK-TUBA1C [cytosol] (R-HSA-5618314) Ac K40 TUBA1C [axonemal microtubule] (R-HSA-5624856) TUBA1C folding intermediate [cytosol] (R-HSA-392798) TUBA1C unfolded [cytosol] (R-HSA-392772) L-isoglutamyl polyglycyl-TUBA1C [cytosol] (R-HSA-8867405) Polyglutamyl-TUBA1C [cytosol] (R-HSA-8867401) TUBA1C(1-448) [cytosol] (R-HSA-8955579) TUBA1C [axonemal microtubule] (R-HSA-5610439) TUBA1C [cytosol] (R-HSA-190590)	0.556	3
UniProt:O14901 KLF11			0.556	3
UniProt:Q9H9J2 MRPL44	1	MRPL44 [mitochondrial inner membrane] (R-HSA-5368245)	0.553	2
UniProt:P02766 TTR	2	TTR [azurophil granule lumen] (R-HSA-6799366) TTR [extracellular region] (R-HSA-976883)	0.553	2
UniProt:P61956 SUMO2	6	lysyl-G93-SUMO2 [cytosol] (R-HSA-9834803) SUMO2(1-95) [nucleoplasm] (R-HSA-2990837) UBA2-G93-SUMO2 [nucleoplasm] (R-HSA-3730618) SUMO2 [nucleoplasm] (R-HSA-2984281) UBE2I-G93-SUMO2 [nucleoplasm] (R-HSA-3730625) lysyl-G93-SUMOyl-K11-SUMO2 [nucleoplasm] (R-HSA-9761546)	0.553	2
UniProt:Q8N6T7 SIRT6	1	SIRT6 [nucleoplasm] (R-HSA-5685963)	0.553	2
UniProt:Q9NRH1 YAE1			0.553	2
UniProt:P15090 FABP4	3	FABP4 [cytosol] (R-HSA-2026069) FABP4 [lipid droplet] (R-HSA-163428) FABP4 [nucleoplasm] (R-HSA-2026072)	0.553	2
UniProt:P31946 YWHAB	1	YWHAB [cytosol] (R-HSA-48888)	0.548	3
UniProt:Q9H2C0 GAN	1	GAN [cytosol] (R-HSA-976014)	0.527	2
UniProt:Q8IWV7 UBR1	1	UBR1 [cytosol] (R-HSA-976040)	0.527	2
UniProt:P14735 IDE	5	IDE [mitochondrial outer membrane] (R-HSA-5696861) PolyUb-IDE [mitochondrial outer membrane] (R-HSA-6783095) IDE [peroxisomal matrix] (R-HSA-9033157) IDE [cytosol] (R-HSA-9033133) IDE [endosome lumen] (R-HSA-9794504)	0.527	2
UniProt:Q925J2 Q925J2			0.527	2
UniProt:Q92731 ESR2	5	PalmS-ESR2 [cytosol] (R-HSA-9020979) Me-PalmS-ESR2 [plasma membrane] (R-HSA-9637787) PalmS-ESR2 [plasma membrane] (R-HSA-9021059) ESR2 [nucleoplasm] (R-HSA-446165) ESR2 [cytosol] (R-HSA-9020970)	0.527	3
UniProt:Q9H7C4-2 SYNC			0.527	2
UniProt:Q9H0A0 NAT10	1	NAT10 [nucleoplasm] (R-HSA-6791008)	0.527	2
UniProt:Q96DX4 RSPRY			0.527	2
UniProt:P0DTC2 S	20	S(686-815) [plasma membrane] (R-COV-9770188) Spike S2' Fragment [plasma membrane] (R-COV-9770189) S1 [plasma membrane] (R-COV-9769950) fully glycosylated Spike [plasma membrane] (R-COV-9733472) nascent Spike [endoplasmic reticulum lumen] (R-COV-9694796) 14-sugar N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9694459) Man(9) N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696892) high-mannose N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696875) high-mannose N-glycan folded Spike [endoplasmic reticulum lumen] (R-COV-9696880) high-mannose N-glycan folded Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9766369) high-mannose N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696943) di-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696920) tri-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9697006) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696997) complex N-glycan-PALM-Spike S2 Fragment [plasma membrane] (R-COV-9769952) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9698330) fully glycosylated Spike [virion membrane] (R-COV-9698327) complex N-glycan-PALM-Spike S1 Fragment [endocytic vesicle membrane] (R-COV-9694745) complex N-glycan-PALM-Spike S2 Fragment [endocytic vesicle membrane] (R-COV-9694343) complex N-glycan-PALM-Spike S2 Fragment [virion membrane] (R-COV-9694791)	0.524	4
UniProt:P63172 DYNLT1	3	DYNLT1 [secretory granule lumen] (R-HSA-6801497) DYNLT1 [extracellular region] (R-HSA-6806509) DYNLT1 [ficolin-1-rich granule lumen] (R-HSA-6801487)	0.508	2
UniProt:Q9C0D3 ZY11B			0.508	2
UniProt:Q99873 PRMT1	2	PRMT1 [cytosol] (R-HSA-9632173) PRMT1 [nucleoplasm] (R-HSA-3215140)	0.508	2
UniProt:P16278 GLB1	8	GLB1 W509C [lysosomal lumen] (R-HSA-2262732) GLB1 Y83C [lysosomal lumen] (R-HSA-2262735) GLB1 R482C [lysosomal lumen] (R-HSA-2262739) GLB1 W273L [lysosomal lumen] (R-HSA-2262738) GLB1 [ficolin-1-rich granule lumen] (R-HSA-6800968) GLB1 [lysosomal lumen] (R-HSA-1605623) GLB1 [azurophil granule lumen] (R-HSA-6799124) GLB1 [extracellular region] (R-HSA-6806213)	0.508	2
UniProt:P11021 HSPA5	6	HSPA5 [extracellular region] (R-HSA-351322) HSPA5 [endoplasmic reticulum lumen] (R-HSA-387190) HSPA5 [endoplasmic reticulum membrane] (R-HSA-351315) HSPA5 [cytosol] (R-HSA-5252115) HSPA5 [nucleoplasm] (R-HSA-5252042) HSPA5 [lumenal side of endoplasmic reticulum membrane] (R-HSA-985498)	0.508	3
UniProt:P10619 CTSA	7	CTSA(29-480) [lysosomal lumen] (R-HSA-1181230) CTSA(29-326) [extracellular region] (R-HSA-6806187) CTSA(327-480) [extracellular region] (R-HSA-6806233) CTSA(29-326) [azurophil granule lumen] (R-HSA-6799135) CTSA(327-480) [azurophil granule lumen] (R-HSA-6799120) CTSA(29-326) [lysosomal lumen] (R-HSA-1605735) CTSA(327-480) [lysosomal lumen] (R-HSA-1605642)	0.508	2
UniProt:Q14457 BECN1	4	K63polyUb-BECN1 [cytosol] (R-HSA-6782989) ISG15-K-BECN1 [cytosol] (R-HSA-9853030) p-S15-BECN1 [cytosol] (R-HSA-5682391) BECN1 [cytosol] (R-HSA-1632841)	0.499	3
UniProt:P51451 BLK	2	MyrG2-BLK [plasma membrane] (R-HSA-9606871) BLK [cytosol] (R-HSA-983580)	0.499	3
UniProt:O95361 TRI16			0.463	3
UniProt:Q8UZC1 Q8UZC1			0.463	2

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