Caspase-mediated cleavage of Acinus

Stable Identifier
R-HSA-201630
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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Caspase-mediated cleavage of Acinus
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Acinus induces apoptotic chromatin condensation after cleavage and activation by CASP3 (Sahara et al., 1999).
Literature References
PubMed ID Title Journal Year
10490026 Acinus is a caspase-3-activated protein required for apoptotic chromatin condensation

Sahara, S, Imamoto, N, Yoneda, Y, Aoto, M, Eguchi, Y, Tsujimoto, Y

Nature 1999
Participants
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Output
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as an event of
Catalyst Activity

cysteine-type endopeptidase activity of Caspase-3 [cytosol]

Physical Entity
Caspase-3 [cytosol] (Homo sapiens)
Activity
cysteine-type endopeptidase activity (GO:0004197)
Orthologous Events
Caspase-mediated cleavage of Acinus (Bos taurus)
Caspase-mediated cleavage of Acinus (Caenorhabditis elegans)
Caspase-mediated cleavage of Acinus (Canis familiaris)
Caspase-mediated cleavage of Acinus (Drosophila melanogaster)
Caspase-mediated cleavage of Acinus (Mus musculus)
Caspase-mediated cleavage of Acinus (Rattus norvegicus)
Caspase-mediated cleavage of Acinus (Sus scrofa)
Authored
Schulze-Osthoff, K  (2007-09-03)
Reviewed
Ranganathan, S  (2007-11-23)
Created
Matthews, L  (2007-09-03)
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