PPP3 complex dephosphorylates DARPP-32 on Thr34

Stable Identifier
R-HSA-201787
Type
Reaction [transition]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
5/5
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PPP3 complex dephosphorylates DARPP-32 on Thr34
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Calcineurin has been identified as a Ca2+- and calmodulin-dependent phosphoprotein phosphatase. The concentration of the enzyme is relatively high in mammalian brain.
Literature References
PubMed ID Title Journal Year
6330098 Mammalian brain phosphoproteins as substrates for calcineurin

King, MM, Chan, KF, Hemmings HC, Jr, Huang, CY, Chock, PB, Greengard, P, Nairn, AC

J Biol Chem 1984
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Catalyst Activity

protein serine/threonine phosphatase activity of PPP3 complex [cytosol]

Physical Entity
PPP3 complex [cytosol] (Homo sapiens)
Activity
protein serine/threonine phosphatase activity (GO:0004722)
Inferred From
Ppp3 complex dephosphorylates DARPP-32 on T34 (Rattus norvegicus)
Authored
Jassal, B  (2004-03-31)
Le Novere, N  (2004-03-31)
Reviewed
Castagnoli, L  (2008-11-06)
Created
Jassal, B  (2007-09-20)
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