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G-actin [cytosol]
Stable Identifier
R-HSA-201857
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Synonyms
actin:ATP
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Homo sapiens)
Cell junction organization (Homo sapiens)
Cell-cell junction organization (Homo sapiens)
Adherens junctions interactions (Homo sapiens)
Interaction of Afadin with F-actin (Homo sapiens)
Afadin:F-actin [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Cell-extracellular matrix interactions (Homo sapiens)
MigFilin associates with Filamin and F-actin (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Migfilin:Filamin A:F-actin [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
EPH-Ephrin signaling (Homo sapiens)
EPHB-mediated forward signaling (Homo sapiens)
N-WASP binds ARP2/3 and G-actin (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
L1CAM interactions (Homo sapiens)
Interaction between L1 and Ankyrins (Homo sapiens)
Ankyrins link voltage-gated sodium and potassium channels to spectrin and L1 (Homo sapiens)
NFASC:NRCAM:ANK1-3:SPTA:SPTB:F-actin [plasma membrane] (Homo sapiens)
SPTA:SPTB:F-actin [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
NFASC:NRCAM:ANK1-3:SPTA:SPTB:F-actin:KCNQ2,3, SCNAs:SCNBs [plasma membrane] (Homo sapiens)
NFASC:NRCAM:ANK1-3:SPTA:SPTB:F-actin [plasma membrane] (Homo sapiens)
SPTA:SPTB:F-actin [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
L1 linked to actin cytoskeleton by ankyrin (Homo sapiens)
L1 dimer:Ankyrin:Spectrin:F-actin [plasma membrane] (Homo sapiens)
SPTA:SPTB:F-actin [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
SPTA:SPTB:F-actin [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Recycling pathway of L1 (Homo sapiens)
Dephosphorylation of pL1 (Y1176) (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
pL1:ERM:F-actin [plasma membrane] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Linkage of L1 with treadmilling F-actin (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
pL1:ERM:F-actin [plasma membrane] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Shootin-1 links L1 and retrograde actin flow (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
pL1:Shootin-1:F-actin [plasma membrane] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Parasite infection (Homo sapiens)
Leishmania phagocytosis (Homo sapiens)
FCGR3A-mediated phagocytosis (Homo sapiens)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Branching and elongation of mother and daughter filaments (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Homo sapiens)
Actin filament bound Myosin-X [plasma membrane] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Myosin-Actin filaments [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
Regulation of actin dynamics for phagocytic cup formation (Homo sapiens)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Branching and elongation of mother and daughter filaments (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Homo sapiens)
Actin filament bound Myosin-X [plasma membrane] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Role of myosins in phagosome formation (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Myosin-Actin filaments [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by VEGF (Homo sapiens)
VEGFA-VEGFR2 Pathway (Homo sapiens)
p-MAPK2/3 phosphorylates HSP27 (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
HSP27 oligomer:F-actin [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases Activate Formins (Homo sapiens)
Activated FMNL3 binds G-actin (Homo sapiens)
Profilin:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
RHOC:GTP:FMNL3:G-actin [plasma membrane] (Homo sapiens)
Profilin:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Association of profilin with monomeric actin (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Profilin:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
CDC42:GTP:FMNL2 binds Profilin:G-actin (Homo sapiens)
CDC42:FMNL2:Profilin:G-actin [plasma membrane] (Homo sapiens)
Profilin:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Profilin:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Profilin:G-actin binds MKL1 (Homo sapiens)
Profilin:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Profilin:G-actin:MKL1 [cytosol] (Homo sapiens)
Profilin:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
RAC1:GTP:FMNL1 binds profilin:G-actin (Homo sapiens)
Profilin:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Homo sapiens)
Profilin:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
RHOA:GTP:DIAPH1 binds EVL and sequesters profilin:G-actin from MKL1 (Homo sapiens)
Profilin:G-actin:MKL1 [cytosol] (Homo sapiens)
Profilin:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
RHOA:GTP:DIAPH1:EVL:Profilin:G-actin [plasma membrane] (Homo sapiens)
Profilin:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
SRGAP2 binds RAC1:GTP:FMNL1:profilin:G-actin (Homo sapiens)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Homo sapiens)
Profilin:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Homo sapiens)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Homo sapiens)
Profilin:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
SRGAP2 stimulates RAC1 GTP-ase activity and ends FMNL1-mediated elongation of actin filaments (Homo sapiens)
Profilin:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
SRGAP2:RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Homo sapiens)
RAC1:GTP:FMNL1:Profilin:G-actin [plasma membrane] (Homo sapiens)
Profilin:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
RHO GTPases Activate WASPs and WAVEs (Homo sapiens)
(WASPs, WAVE):G-actin:ARP2/3 binds F-actin (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Branching and elongation of mother and daughter filaments (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Mother filament:branching complex:daughter filament [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Mother filament:branching complex [cytosol] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
RHO GTPases activate IQGAPs (Homo sapiens)
IQGAPs bind F-actin, which is inhibited by calmodulin (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
RAC1,CDC42:GTP:IQGAP:F-actin [plasma membrane] (Homo sapiens)
F-actin [cytosol] (Homo sapiens)
G-actin [cytosol] (Homo sapiens)
Participants
components
actin [cytosol]
(Homo sapiens)
ATP [cytosol]
Participates
as a component of
p-EPHBs:EFNBs:ITSN1:N-WASP:CDC42:GTP:PI(4,5)P2:ARP2/3;G-actin [plasma membrane] (Homo sapiens)
WAVE2, WASP, N-WASP:ARP2/3 complex:G-actin [cytosol] (Homo sapiens)
Profilin:G-actin [cytosol] (Homo sapiens)
as an input of
N-WASP binds ARP2/3 and G-actin (Homo sapiens)
Branching and elongation of mother and daughter filaments (Homo sapiens)
WASPs or WAVEs activate the ARP2/3 complex (Homo sapiens)
Association of profilin with monomeric actin (Homo sapiens)
as a repeated unit of
F-actin [cytosol] (Homo sapiens)
Inferred To
G-actin [cytosol]
(Bos taurus)
G-actin [cytosol]
(Caenorhabditis elegans)
G-actin [cytosol]
(Canis familiaris)
G-actin [cytosol]
(Danio rerio)
G-actin [cytosol]
(Dictyostelium discoideum)
G-actin [cytosol]
(Drosophila melanogaster)
G-actin [cytosol]
(Gallus gallus)
G-actin [cytosol]
(Mus musculus)
G-actin [cytosol]
(Rattus norvegicus)
G-actin [cytosol]
(Saccharomyces cerevisiae)
G-actin [cytosol]
(Schizosaccharomyces pombe)
G-actin [cytosol]
(Sus scrofa)
G-actin [cytosol]
(Xenopus tropicalis)
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