Reactome | p-T,p-S-AKT [cytosol]

p-T,p-S-AKT [cytosol]

Stable Identifier

R-HSA-202074

Type

Set [CandidateSet]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Active AKT

Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - SARS-CoV-2 Infection (Homo sapiens)
        
        SARS-CoV-2-host interactions (Homo sapiens)
        
        SARS-CoV-2 targets host intracellular signalling and regulatory pathways (Homo sapiens)
        
        PDPK1 phosphorylates AKT at T308 (Homo sapiens)
        
        p-T,p-S-AKT [cytosol] (Homo sapiens)

Programmed Cell Death (Homo sapiens)

- Apoptosis (Homo sapiens)
  - Intrinsic Pathway for Apoptosis (Homo sapiens)
    - Activation of BH3-only proteins (Homo sapiens)
      - Activation of BAD and translocation to mitochondria (Homo sapiens)
        
        AKT phosphorylates BAD (Homo sapiens)
        
        p-T,p-S-AKT [cytosol] (Homo sapiens)

Participants

members

p-T308,S473-AKT1 [cytosol] (Homo sapiens)

candidates

Participates

as an input of

as an output of

PDPK1 phosphorylates AKT at T308 (Homo sapiens)

This entity regulates

Positively

NFE2L2 translocates from cytosol to nucleoplasm (Homo sapiens)

Inferred To

p-T,p-S-AKT [cytosol] (Caenorhabditis elegans)

p-T,p-S-AKT [cytosol] (Danio rerio)

p-T,p-S-AKT [cytosol] (Dictyostelium discoideum)

p-T,p-S-AKT [cytosol] (Drosophila melanogaster)

p-T,p-S-AKT [cytosol] (Mus musculus)

p-T,p-S-AKT [cytosol] (Rattus norvegicus)

p-T,p-S-AKT [cytosol] (Saccharomyces cerevisiae)

p-T,p-S-AKT [cytosol] (Schizosaccharomyces pombe)

phospho-AKT1 [cytosol] (Gallus gallus)

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