Reactome | NOSTRIN [plasma membrane]

NOSTRIN [plasma membrane]

Stable Identifier

R-HSA-202134

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8IVI9 NOSTRIN

Gene Names

NOSTRIN

Chain

chain:1-506

Reference Genes

BioGPS Gene:115677 NOSTRIN

COSMIC (genes):NOSTRIN NOSTRIN

CTD Gene:115677 NOSTRIN

dbSNP Gene:115677 NOSTRIN

ENSEMBL:ENSG00000163072 NOSTRIN

HGNC:20203 NOSTRIN

KEGG:hsa:115677 NOSTRIN

Monarch:115677 NOSTRIN

NCBI Gene:115677 NOSTRIN

OMIM:607496 NOSTRIN

UCSC:Q8IVI9 NOSTRIN

Reference Transcript

Other Identifiers

115677

11735764_a_at

16887194

226992_PM_at

226992_at

2514217

2514218

2514219

2514220

2514221

2514223

2514224

2514228

2514230

2514231

2514233

2514234

2514236

2514238

2514239

2514241

2514242

2514243

2514244

2514247

2514248

2514249

2514250

2514251

2514252

2514255

2514256

2514258

2514259

2514260

2514262

2514263

2514264

56167_at

8046099

82538_at

A_14_P129453

A_23_P79360

GO:0003677

GO:0005515

GO:0005634

GO:0005737

GO:0005856

GO:0005886

GO:0006355

GO:0006897

GO:0007015

GO:0007165

GO:0016192

GO:0016477

GO:0030666

GO:0031410

GO:0043226

GO:0045892

GO:0048870

HMNXSV003013307

HMNXSV003018235

HMNXSV003022633

Hs.10260.0.A1_3p_at

ILMN_1670099

PH_hs_0025048

TC02000998.hg

Participates

as a component of

NOSTRIN homotrimer [plasma membrane] (Homo sapiens)

Other forms of this molecule

NOSTRIN [endocytic vesicle membrane]

Inferred To

Nostrin [plasma membrane] (Mus musculus)

Nostrin [plasma membrane] (Rattus norvegicus)

cdap-2 [plasma membrane] (Caenorhabditis elegans)

Ghost homologue of NOSTRIN [plasma membrane] (Bos taurus)

Ghost homologue of NOSTRIN [plasma membrane] (Gallus gallus)

NOSTRIN [plasma membrane] (Canis familiaris)

NOSTRIN [plasma membrane] (Sus scrofa)

cindr [plasma membrane] (Drosophila melanogaster)

nostrin [plasma membrane] (Danio rerio)

Cross References

RefSeq

NP_001165103.1, NP_001165102.1, NP_443178.2, NP_001034813.2

ENSEMBL

ENST00000397209, ENST00000458381, ENST00000444448, ENST00000317647, ENSP00000318921, ENSP00000402140, ENST00000397206, ENSP00000394051, ENSP00000380392, ENSP00000380390, ENST00000445023, ENSP00000404413

OpenTargets

ENSG00000163072

HPA

ENSG00000163072-NOSTRIN

PRO

Q8IVI9

Pharos - Targets

Q8IVI9

PDB

2YUN

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P29474 NOS3	9	2xPalmC-MyrG-p-S1177-NOS3 [plasma membrane] (R-HSA-202139) 2xPalmC-MyrG-NOS3 [plasma membrane] (R-HSA-534993) 2xPalmC-MyrG-NOS3 [Golgi membrane] (R-HSA-203769) MyrG-NOS3 [cytosol] (R-HSA-203687) MyrG-NOS3 [Golgi membrane] (R-HSA-534995) NOS3 [cytosol] (R-HSA-202114) 2xPalmC-MyrG-NOS3 [endocytic vesicle membrane] (R-HSA-535007) 2xPalmC-MyrG-p-S633-NOS3 [plasma membrane] (R-HSA-9861341) 2xPalmC-MyrG-p-S1177,S1179-NOS3 [plasma membrane] (R-HSA-9860783)	0.729	9
UniProt:P11362 FGFR1	9	FGFR1 [plasma membrane] (R-HSA-9756433) p-8Y- FGFR1 R576W [plasma membrane] (R-HSA-2023361) p-8Y-FGFR1 N546K [plasma membrane] (R-HSA-2023358) p-8Y-FGFR1 K656E [plasma membrane] (R-HSA-2023356) p-6Y-FGFR1(22-763):TACC1(571-805) fusion [plasma membrane] (R-HSA-8853142) FGFR1 R576W [plasma membrane] (R-HSA-2011844) FGFR1 N546K [plasma membrane] (R-HSA-1614377) FGFR1 K656E [plasma membrane] (R-HSA-1614373) FGFR1(22-763):TACC1(571-805) fusion [plasma membrane] (R-HSA-8853241)	0.633	5
UniProt:Q05193 DNM1	3	DNM1 [plasma membrane] (R-HSA-177488) DNM1 [lysosomal membrane] (R-HSA-196150) DNM1 [cytosol] (R-HSA-2213182)	0.524	3

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