Reactome | PLCD3 [plasma membrane]

PLCD3 [plasma membrane]

Stable Identifier

R-HSA-2023882

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

KIAA1964

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8N3E9 PLCD3

Gene Names

PLCD3, KIAA1964

Chain

chain:1-789

Reference Genes

BioGPS Gene:113026 PLCD3

COSMIC (genes):PLCD3 PLCD3

CTD Gene:113026 PLCD3

dbSNP Gene:113026 PLCD3

ENSEMBL:ENSG00000161714 PLCD3

ENSEMBL_homo_sapiens_GENE:ENSG00000161714.12 PLCD3

HGNC:9061 PLCD3

KEGG Gene (Homo sapiens):113026 PLCD3

Monarch:113026 PLCD3

NCBI Gene:113026 PLCD3

OMIM:608795 PLCD3

UCSC:Q8N3E9 PLCD3

Reference Transcript

RefSeq:NM_133373.4 PLCD3

Other Identifiers

113026

11754952_x_at

1552476_3p_s_at

1552476_PM_s_at

1552476_s_at

16845826

234971_3p_x_at

234971_PM_x_at

234971_x_at

3759580

3759582

3759584

3759586

3759588

3759589

3759590

3759591

3759592

3759593

3759594

3759595

3759596

3759598

3759599

3759600

3759601

3759602

3759603

3759604

3759605

3759606

3759607

3759610

3759611

3759612

3759616

3759617

8016168

A_23_P351757

GE86096

GO:0001525

GO:0003824

GO:0004435

GO:0005634

GO:0005654

GO:0005737

GO:0005886

GO:0006629

GO:0007165

GO:0008081

GO:0016020

GO:0016042

GO:0016787

GO:0023052

GO:0032154

GO:0035556

GO:0042127

GO:0043226

GO:0046872

GO:0048856

GO:0060716

HMNXSV003038615

Hs.95110.0.S1_3p_s_at

Hs2.380094.1.S1_3p_s_at

ILMN_1722798

PH_hs_0035874

TC17001592.hg

Participates

as a component of

PLCD3:Ca2+ [plasma membrane] (Homo sapiens)

Inferred To

plc-3 [plasma membrane] (Caenorhabditis elegans)

Plcd3 [plasma membrane] (Rattus norvegicus)

PLCD3 [plasma membrane] (Bos taurus)

PLCD3 [plasma membrane] (Canis familiaris)

PLCD3 [plasma membrane] (Danio rerio)

PLCD3 [plasma membrane] (Dictyostelium discoideum)

PLCD3 [plasma membrane] (Gallus gallus)

PLCD3 [plasma membrane] (Mus musculus)

PLCD3 [plasma membrane] (Plasmodium falciparum)

PLCD3 [plasma membrane] (Saccharomyces cerevisiae)

PLCD3 [plasma membrane] (Schizosaccharomyces pombe)

PLCD3 [plasma membrane] (Sus scrofa)

plc-4 [plasma membrane] (Caenorhabditis elegans)

Homologues of PLCD3 [plasma membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_588614.1

Guide to Pharmacology - Targets

1410

OpenTargets

ENSG00000161714

HPA

ENSG00000161714-PLCD3

GeneCards

Q8N3E9

Ensembl

ENST00000619929, ENSP00000479636, ENSG00000161714

PRO

Q8N3E9

Pharos - Targets

Q8N3E9

HMDB Protein

HMDBP04457

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96JC9 EAF1	1	EAF1 [nucleoplasm] (R-HSA-8932787)	0.527	3
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	7

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