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PLCE1 [plasma membrane]
Stable Identifier
R-HSA-2023890
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
KIAA1516, PLCE, PPLC
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Inositol phosphate metabolism (Homo sapiens)
Synthesis of IP3 and IP4 in the cytosol (Homo sapiens)
PI(4,5)P2 is hydrolysed to I(1,4,5)P3 and DAG by tethered PLC[1] at the plasma membrane (Homo sapiens)
PLCdegh [plasma membrane] (Homo sapiens)
PLCE1:Ca2+ [plasma membrane] (Homo sapiens)
PLCE1 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9P212 PLCE1
Gene Names
PLCE1, KIAA1516, PLCE, PPLC
Chain
chain:1-2302
Reference Genes
BioGPS Gene:51196 PLCE1
COSMIC (genes):PLCE1 PLCE1
CTD Gene:51196 PLCE1
dbSNP Gene:51196 PLCE1
ENSEMBL:ENSG00000138193 PLCE1
ENSEMBL_homo_sapiens_GENE:ENSG00000138193.17 PLCE1
HGNC:17175 PLCE1
KEGG Gene (Homo sapiens):51196 PLCE1
Monarch:51196 PLCE1
NCBI Gene:51196 PLCE1
OMIM:608414 PLCE1
UCSC:Q9P212 PLCE1
Reference Transcript
RefSeq:NM_001165979.2 PLCE1
RefSeq:NM_001288989.1 PLCE1
RefSeq:NM_016341.3 PLCE1
Other Identifiers
11721977_a_at
11721978_a_at
16707628
16707631
205111_PM_s_at
205111_s_at
205112_PM_at
205112_at
214159_PM_at
214159_at
3258492
3258495
3258496
3258497
3258505
3258506
3258515
3258516
3258533
3258551
3258553
3258554
3258555
3258557
3258563
3258565
3258566
3258573
3258574
3258575
3258576
3258577
3258578
3258580
3258581
3258582
3258584
3258589
3258593
3258594
3258595
3258596
3258597
3258598
3258599
3258601
3258604
3258606
3258607
3258610
3258611
3258612
3258613
3258614
3258615
3258616
3258617
3258838
3258840
3258842
3258844
40330_at
51196
66162_at
7929388
A_14_P113903
A_14_P126119
A_14_P128859
A_14_P129236
A_14_P136931
A_21_P0006897
A_23_P35617
A_33_P3346669
GE58726
GO:0000139
GO:0003824
GO:0004435
GO:0004629
GO:0005085
GO:0005515
GO:0005737
GO:0005794
GO:0005829
GO:0005886
GO:0006629
GO:0006651
GO:0007165
GO:0007173
GO:0007200
GO:0007264
GO:0007265
GO:0008081
GO:0010592
GO:0016020
GO:0016042
GO:0016787
GO:0019722
GO:0019899
GO:0023052
GO:0030027
GO:0031267
GO:0032835
GO:0035556
GO:0042995
GO:0043226
GO:0046872
GO:0048015
GO:0048856
GO:0051209
GO:0055065
GO:0055085
GO:0098772
HMNXSV003002563
HMNXSV003033980
HMNXSV003051980
ILMN_1784447
PH_hs_0022254
TC10000670.hg
g7705940_3p_s_at
p18190
Participates
as a component of
PLCE1:Ca2+ [plasma membrane] (Homo sapiens)
Inferred To
plc-1 [plasma membrane]
(Caenorhabditis elegans)
PLCE1 [plasma membrane]
(Bos taurus)
PLCE1 [plasma membrane]
(Canis familiaris)
PLCE1 [plasma membrane]
(Dictyostelium discoideum)
PLCE1 [plasma membrane]
(Gallus gallus)
PLCE1 [plasma membrane]
(Plasmodium falciparum)
PLCE1 [plasma membrane]
(Saccharomyces cerevisiae)
PLCE1 [plasma membrane]
(Schizosaccharomyces pombe)
PLCE1 [plasma membrane]
(Sus scrofa)
Plce1 [plasma membrane]
(Mus musculus)
Plce1 [plasma membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_057425.3
,
NP_001275918.1
,
NP_001159451.1
Guide to Pharmacology - Targets
1412
OpenTargets
ENSG00000138193
GeneCards
Q9P212
HPA
ENSG00000138193-PLCE1
Ensembl
ENST00000371380
,
ENSP00000360431
,
ENST00000675218
,
ENSP00000501910
,
ENSG00000138193
,
ENSP00000360426
,
ENST00000371375
PRO
Q9P212
Pharos - Targets
Q9P212
Orphanet
17292
HMDB Protein
HMDBP04456
PDB
2C5L
,
2BYF
,
2BYE
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