FABP1 [cytosol]

Stable Identifier
R-HSA-2026981
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Fatty acid-binding protein, liver, FABPL_HUMAN
Icon
FABP1 [cytosol] icon
FABP1 [cytosol] icon
Locations in the PathwayBrowser
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General
As inferred from mouse, FABP1 localizes to the nucleus where it may deliver lipids to PPARA.
Literature References
PubMed ID Title Journal Year
11226238 Fatty acids and hypolipidemic drugs regulate peroxisome proliferator-activated receptors alpha - and gamma-mediated gene expression via liver fatty acid binding protein: a signaling path to the nucleus

Borrmann, CM, Wolfrum, C, Borchers, T, Spener, F

Proc Natl Acad Sci U S A 2001
19289416 L-FABP directly interacts with PPARalpha in cultured primary hepatocytes

Payne, HR, Storey, SM, Hostetler, HA, Schroeder, F, Kier, AB, McIntosh, AL, Atshaves, BP

J Lipid Res 2009
External Reference Information
External Reference
UniProt:P07148 FABP1
Gene Names
FABP1, FABPL
Chain
chain:1-127
Reference Genes
BioGPS Gene:2168 FABP1
COSMIC (genes):FABP1 FABP1
CTD Gene:2168 FABP1
dbSNP Gene:2168 FABP1
ENSEMBL:ENSG00000163586 FABP1
ENSEMBL_homo_sapiens_GENE:ENSG00000163586.10 FABP1
HGNC:3555 FABP1
KEGG Gene (Homo sapiens):2168 FABP1
Monarch:2168 FABP1
NCBI Gene:2168 FABP1
OMIM:134650 FABP1
Reference Transcript
Other Identifiers
11723040_a_at
11723041_s_at
11758878_x_at
16900030
205892_PM_s_at
205892_s_at
2168
2563539
2563540
2563546
2563548
2563554
2563555
38586_at
8053654
A_23_P79562
GE81021
GO:0003682
GO:0005215
GO:0005324
GO:0005504
GO:0005515
GO:0005543
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005737
GO:0005777
GO:0005782
GO:0005829
GO:0006629
GO:0008289
GO:0012501
GO:0015908
GO:0015909
GO:0016209
GO:0022600
GO:0032000
GO:0032052
GO:0032991
GO:0043066
GO:0043154
GO:0043226
GO:0045179
GO:0050892
GO:0070062
GO:0070301
GO:0070538
GO:0071456
GO:0098754
GO:0098869
GO:1901363
HMNXSV003007276
ILMN_1678965
M10050_at
PH_hs_0018467
TC02002069.hg
TC02004392.hg
g4557576_3p_at
g4557576_3p_s_at
Participates
as a member of
Other forms of this molecule
FABP1 [nucleoplasm]
Inferred To
LFABP [cytosol] (Gallus gallus)
lbp-8 [cytosol] (Caenorhabditis elegans)
Fabp1 [cytosol] (Mus musculus)
Homologues of FABP1 [cytosol] (Caenorhabditis elegans)
fabp1b.1 [cytosol] (Danio rerio)
FABP1 [cytosol] (Bos taurus)
FABP1 [cytosol] (Caenorhabditis elegans)
FABP1 [cytosol] (Canis familiaris)
FABP1 [cytosol] (Rattus norvegicus)
fabp [cytosol] (Drosophila melanogaster)
lbp-7 [cytosol] (Caenorhabditis elegans)
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
GeneCards
HPA
ZINC target
Ensembl
PRO
Pharos - Targets
PDB
Interactors (2)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P21333-2 FLNA      0.556 3
 UniProt:FLNA Q5HY54      0.556 3
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