Reactome | JAM3 dimerises

JAM3 dimerises

Stable Identifier

R-HSA-202731

Type

Reaction [binding]

Species

Homo sapiens

Compartment

plasma membrane

ReviewStatus

5/5

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JAM-C has been detected in epithelial-cell desmosomes. JAM-C homodimers are prominently located in endothelial-cell tight junctions.

Literature References

PubMed ID	Title	Journal	Year
17099249	JAM-C regulates tight junctions and integrin-mediated cell adhesion and migration Imhof, BA, Aurrand-Lions, M, Iden, S, Mandicourt, G, Ebnet, K	J Biol Chem	2007
17525755	The role of junctional adhesion molecules in vascular inflammation Weber, C, Fraemohs, L, Dejana, E	Nat Rev Immunol	2007