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LATS2 [cytosol]
Stable Identifier
R-HSA-2028580
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Serine/threonine-protein kinase LATS2, WARTS-like protein kinase
Icon
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Hippo (Homo sapiens)
KIBRA (WWC1) binds LATS proteins (Homo sapiens)
KIBRA:LATS [cytosol] (Homo sapiens)
LATS [cytosol] (Homo sapiens)
LATS2 [cytosol] (Homo sapiens)
LATS [cytosol] (Homo sapiens)
LATS2 [cytosol] (Homo sapiens)
NPHP4 protein binds LATS proteins (Homo sapiens)
LATS [cytosol] (Homo sapiens)
LATS2 [cytosol] (Homo sapiens)
NPHP4:LATS [cytosol] (Homo sapiens)
LATS [cytosol] (Homo sapiens)
LATS2 [cytosol] (Homo sapiens)
Phosphorylated MOB1A proteins associate with LATS proteins (Homo sapiens)
LATS [cytosol] (Homo sapiens)
LATS2 [cytosol] (Homo sapiens)
LATS:p-MOB [cytosol] (Homo sapiens)
LATS [cytosol] (Homo sapiens)
LATS2 [cytosol] (Homo sapiens)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Homo sapiens)
LATS:p-MOB [cytosol] (Homo sapiens)
LATS [cytosol] (Homo sapiens)
LATS2 [cytosol] (Homo sapiens)
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Homo sapiens)
LATS:p-MOB [cytosol] (Homo sapiens)
LATS [cytosol] (Homo sapiens)
LATS2 [cytosol] (Homo sapiens)
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Homo sapiens)
LATS:p-MOB [cytosol] (Homo sapiens)
LATS [cytosol] (Homo sapiens)
LATS2 [cytosol] (Homo sapiens)
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Homo sapiens)
LATS:p-MOB [cytosol] (Homo sapiens)
LATS [cytosol] (Homo sapiens)
LATS2 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NRM7 LATS2
Gene Names
LATS2, KPM
Chain
chain:1-1088
Reference Genes
BioGPS Gene:26524 LATS2
COSMIC (genes):LATS2 LATS2
CTD Gene:26524 LATS2
dbSNP Gene:26524 LATS2
ENSEMBL:ENSG00000150457 LATS2
HGNC:6515 LATS2
KEGG:hsa:26524 LATS2
Monarch:26524 LATS2
NCBI Gene:26524 LATS2
OMIM:604861 LATS2
UCSC:Q9NRM7 LATS2
Reference Transcript
RefSeq:NM_014572.2 LATS2
RefSeq:XM_005266342.1 LATS2
Other Identifiers
11721738_a_at
11721739_a_at
11755581_a_at
16777259
223379_PM_s_at
223379_s_at
223380_PM_s_at
223380_s_at
227013_PM_at
227013_at
26524
3504527
3504528
3504529
3504530
3504532
3504535
3504537
3504538
3504539
3504540
3504541
3504542
3504543
3504544
3504545
3504546
3504547
3504549
3504564
3504574
3504575
3504576
3504577
60514_at
7970498
83093_at
A_23_P204958
A_24_P70002
GE53689
GO:0000082
GO:0000922
GO:0001827
GO:0001828
GO:0003824
GO:0004672
GO:0004674
GO:0005515
GO:0005524
GO:0005634
GO:0005737
GO:0005813
GO:0005815
GO:0005829
GO:0005856
GO:0006468
GO:0007165
GO:0008104
GO:0009755
GO:0016740
GO:0017015
GO:0030154
GO:0030216
GO:0034451
GO:0035329
GO:0035556
GO:0043065
GO:0043226
GO:0045736
GO:0046620
GO:0046872
GO:0051301
GO:0060070
GO:0090090
GO:0106310
GO:0140096
GO:1900181
HMNXSV003020793
Hs.19074.0.S1_3p_a_at
Hs.19074.1.S1_3p_at
ILMN_1703412
PH_hs_0035470
TC13000463.hg
g8886763_3p_a_at
Participates
as a member of
LATS [cytosol] (Homo sapiens)
Other forms of this molecule
p-S872,T1041-LATS2 [cytosol]
Inferred To
LATS2 [cytosol]
(Bos taurus)
LATS2 [cytosol]
(Caenorhabditis elegans)
LATS2 [cytosol]
(Canis familiaris)
LATS2 [cytosol]
(Danio rerio)
LATS2 [cytosol]
(Drosophila melanogaster)
LATS2 [cytosol]
(Gallus gallus)
LATS2 [cytosol]
(Mus musculus)
LATS2 [cytosol]
(Sus scrofa)
Lats2 [cytosol]
(Rattus norvegicus)
Cross References
RefSeq
XP_005266399.1
,
NP_055387.2
ZINC - World Drugs
LATS2_HUMAN
Guide to Pharmacology - Targets
1516
ENSEMBL
ENSP00000372035
,
ENST00000382592
OpenTargets
ENSG00000150457
ZINC - FDA approved
LATS2_HUMAN
ZINC - Substances
LATS2_HUMAN
ZINC - Biogenic
LATS2_HUMAN
ZINC target
Q9NRM7
PRO
Q9NRM7
GlyGen
Q9NRM7
PDB
4ZRI
ZINC - Investigational
LATS2_HUMAN
IntEnz
2.7.11.1
HPA
ENSG00000150457-LATS2
Pharos - Targets
Q9NRM7
ZINC - Predictions - Purchasable
LATS2_HUMAN
HMDB Protein
HMDBP01406
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96IF1 AJUBA
3
AJUBA [nucleoplasm]
(R-HSA-5687935)
p-S-AJUBA [cytosol]
(R-HSA-2574841)
AJUBA [cytosol]
(R-HSA-2564698)
0.714
7
UniProt:O43255 SIAH2
1
SIAH2 [cytosol]
(R-HSA-374566)
0.632
6
UniProt:O95863 SNAI1
1
SNAI1 [nucleoplasm]
(R-HSA-2980903)
0.499
2
UniProt:O75791 GRAP2
1
GRAP2 [cytosol]
(R-HSA-202367)
0.488
2
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