Phosphorylation of YAP by LATS1

Stable Identifier
R-HSA-2028598
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Cytosolic phospho-LATS1, complexed with MOB1, catalyzes the phosphorylation of YAP on five serine residues (Hao et al. 2008).
Literature References
PubMed ID Title Journal Year
18158288 Tumor suppressor LATS1 is a negative regulator of oncogene YAP

Cheung, K, Rashidi, B, Yang, X, Hao, Y, Chun, A

J Biol Chem 2008
Participants
Participates
Catalyst Activity

protein serine/threonine kinase activity of p-LATS1:p-MOB1 [cytosol]

Orthologous Events
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