Reactome | PPAPDC1A [plasma membrane]

PPAPDC1A [plasma membrane]

Stable Identifier

R-HSA-2029082

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Phosphatidate phosphatase PPAPDC1A, PPC1A_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q5VZY2 PLPP4

Gene Names

PLPP4, DPPL2, PPAPDC1, PPAPDC1A

Chain

chain:1-271

Reference Genes

BioGPS Gene:196051 PLPP4

COSMIC (genes):PLPP4 PLPP4

CTD Gene:196051 PLPP4

dbSNP Gene:196051 PLPP4

ENSEMBL:ENSG00000203805 PLPP4

ENSEMBL_homo_sapiens_GENE:ENSG00000203805.11 PLPP4

HGNC:23531 PLPP4

KEGG Gene (Homo sapiens):196051 PLPP4

Monarch:196051 PLPP4

NCBI Gene:196051 PLPP4

UCSC:Q5VZY2 PLPP4

Reference Transcript

Other Identifiers

11728520_a_at

16709936

196051

236044_PM_at

236044_at

237416_PM_at

237416_at

3267590

3267591

3267601

3267602

3267604

3267606

3267607

3267613

3267621

3267622

3267623

3267624

3267625

46372_at

53688_at

7930980

A_24_P810290

GE575009

GE830804

GO:0000810

GO:0001835

GO:0002376

GO:0003824

GO:0005515

GO:0005886

GO:0006629

GO:0006644

GO:0008195

GO:0016020

GO:0016192

GO:0016787

GO:0023052

GO:0038096

GO:0042802

GO:0046839

GO:0048856

GO:0090279

HMNXSV003034203

HMNXSV003056413

Hs.40479.0.A1_3p_at

Hs.65320.0.A1_3p_at

Hs.65320.0.A1_3p_x_at

ILMN_1689177

PH_hs_0003036

TC10000874.hg

Participates

as a member of

Phosphatidate phosphatase [plasma membrane] (Homo sapiens)

Inferred To

Plpp4 [plasma membrane] (Mus musculus)

Plpp4 [plasma membrane] (Rattus norvegicus)

LPP1 [plasma membrane] (Saccharomyces cerevisiae)

PLPP4 [plasma membrane] (Bos taurus)

PLPP4 [plasma membrane] (Canis familiaris)

PLPP4 [plasma membrane] (Sus scrofa)

DPP1 [plasma membrane] (Saccharomyces cerevisiae)

PPAPDC1A [plasma membrane] (Dictyostelium discoideum)

PPAPDC1A [plasma membrane] (Gallus gallus)

dpp1 [plasma membrane] (Schizosaccharomyces pombe)

Homologues of PPAPDC1A [plasma membrane] (Dictyostelium discoideum)

Homologues of PPAPDC1A [plasma membrane] (Saccharomyces cerevisiae)

Dmel\CG12746 [plasma membrane] (Drosophila melanogaster)

plpp4 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_001025230.1, NP_001305095.1, NP_001305097.1, NP_001305098.1, NP_001305096.1

OpenTargets

ENSG00000203805

IntEnz

3.6.1.75

HPA

ENSG00000203805-PLPP4

GeneCards

Q5VZY2

Ensembl

ENST00000398250, ENSG00000203805, ENSP00000381302

PRO

Q5VZY2

Pharos - Targets

Q5VZY2

HMDB Protein

HMDBP07323

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q96BA8 CREB3L1	7	CREB3L1 [Golgi membrane] (R-HSA-8874155) CREB3L1(427-519) [Golgi membrane] (R-HSA-8874139) CREB3L1(1-426) [Golgi membrane] (R-HSA-8874153) CREB3L1 [endoplasmic reticulum membrane] (R-HSA-8874157) CREB3L1(1-375) [cytosol] (R-HSA-8874215) CREB3L1(376-426) [Golgi membrane] (R-HSA-8874213) CREB3L1(1-375) [nucleoplasm] (R-HSA-8874222)	0.556	3
UniProt:P17302 GJA1	6	GJA1 [Golgi membrane] (R-HSA-190649) GJA1 [endoplasmic reticulum membrane] (R-HSA-190654) GJA1 [lysosomal membrane] (R-HSA-196173) p-Y265-GJA1 [plasma membrane] (R-HSA-191657) GJA1 [plasma membrane] (R-HSA-158058) GJA1 [Golgi-associated vesicle membrane] (R-HSA-190544)	0.556	3
UniProt:Q16623 STX1A	5	STX1A [plasma membrane] (R-HSA-449128) STX1A(?-288) [plasma membrane] (R-HSA-5246518) STX1A(1-?) [cytosol] (R-HSA-3065964) STX1A [cytosol] (R-HSA-9609866) STX1A [endoplasmic reticulum membrane] (R-HSA-9609878)	0.556	3
UniProt:O43169 CYB5B	2	CYB5B [endoplasmic reticulum membrane] (R-HSA-9842695) CYB5B [mitochondrial outer membrane] (R-HSA-8943390)	0.556	3
UniProt:P78382 SLC35A1	2	SLC35A1 [Golgi membrane] (R-HSA-727812) SLC35A1 V93Cfs*17 [Golgi membrane] (R-HSA-5651957)	0.556	3
UniProt:Q3SXY8 ARL13B	8	PolyUb-Misfolded ARL13B [lysosomal lumen] (R-HSA-9660004) PolyUb-Misfolded ARL13B [cytosol] (R-HSA-9641129) Ub-Misfolded ARL13B [cytosol] (R-HSA-9641119) Misfolded ARL13B [cytosol] (R-HSA-9640110) Misfolded ARL13B [cilium] (R-HSA-9640116) ARL13B [cilium] (R-HSA-5618181) PolyUb-Misfolded ARL13B [late endosome lumen] (R-HSA-9659986) ARL13B [plasma membrane] (R-HSA-9716787)	0.556	3
UniProt:O95470 SGPL1	1	PXLP-SGPL1 [endoplasmic reticulum membrane] (R-HSA-428661)	0.556	3

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