Reactome | DSG1(889-1049) [cytosol]

DSG1(889-1049) [cytosol]

Stable Identifier

R-HSA-202921

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Desmoglein 1 fragment (889-1049)

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q02413 DSG1

Gene Names

DSG1, CDHF4

Chain

signal peptide:1-23, propeptide:24-49, chain:50-1049

Reference Genes

BioGPS Gene:1828 DSG1

COSMIC (genes):DSG1 DSG1

CTD Gene:1828 DSG1

dbSNP Gene:1828 DSG1

ENSEMBL:ENSG00000134760 DSG1

ENSEMBL_homo_sapiens_GENE:ENSG00000134760.6 DSG1

HGNC:3048 DSG1

KEGG Gene (Homo sapiens):1828 DSG1

Monarch:1828 DSG1

NCBI Gene:1828 DSG1

OMIM:125670 DSG1

UCSC:Q02413 DSG1

Reference Transcript

RefSeq:NM_001942.3 DSG1

Other Identifiers

11739886_at

11739887_at

11747872_a_at

16851708

1828

206642_PM_at

206642_at

3783401

3783402

3783403

3783404

3783405

3783406

3783407

3783408

3783410

3783412

3783413

3783414

3783415

3783416

3783417

3783418

3783420

3783421

3783422

3783423

3783424

3783425

3783426

3783427

3783428

3783429

3783430

3783432

3783434

39586_at

8020724

A_14_P119744

A_33_P3265189

GE79749

GO:0001533

GO:0005509

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0005886

GO:0005911

GO:0007043

GO:0007155

GO:0007156

GO:0009898

GO:0015643

GO:0016020

GO:0016324

GO:0016328

GO:0016339

GO:0022414

GO:0030057

GO:0031410

GO:0032570

GO:0034330

GO:0043226

GO:0045295

GO:0046872

GO:0050821

GO:0060135

GO:0070161

GO:0098609

GO:0101003

HMNXSV003019326

ILMN_1794662

ILMN_1830761

PH_hs_0000347

TC18000124.hg

X56654_at

g4503400_3p_at

Participates

as an output of

Caspase-mediated cleavage of Desmoglein 1 (Homo sapiens)

Other forms of this molecule

DSG1 [cornified envelope]

DSG1 [ficolin-1-rich granule membrane]

DSG1(50-888) [plasma membrane]

DSG1 [plasma membrane]

Inferred To

DSG1(889-1049) [cytosol] (Gallus gallus)

Dsg1 [cytosol] (Rattus norvegicus)

Homologues of DSG1(889-1049) [cytosol] (Sus scrofa)

cdh-4 [cytosol] (Caenorhabditis elegans)

Dsg1a [cytosol] (Mus musculus)

dsg1 [cytosol] (Xenopus tropicalis)

dsg2.1 [cytosol] (Danio rerio)

DSG1 [cytosol] (Bos taurus)

DSG1 [cytosol] (Canis familiaris)

DSG1 [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_001933.2

OpenTargets

ENSG00000134760

GeneCards

Q02413

HPA

ENSG00000134760-DSG1

Ensembl

ENST00000257192, ENSP00000257192, ENSG00000134760

PRO

Q02413

Pharos - Targets

Q02413

Orphanet

15893

HMDB Protein

HMDBP07658

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9NU19 TB22B			0.527	2
UniProt:Q96ER9 MITOK			0.527	2
UniProt:P57076 CF298			0.527	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	5

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