Caspase mediated cleavage of APC

Stable Identifier
R-HSA-202947
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Cleavage of APC by caspase 3 and release of the amino-terminal fragment (1-760) are required for the APC mediated acceleration of apoptosis-associated caspase activity (Qian et al., 2007).
Literature References
Participants
Participates
Catalyst Activity

cysteine-type endopeptidase activity of Caspase-3 [cytosol]

Orthologous Events
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