Reactome | WWTR1 (TAZ), TBX5, and PCAF form a complex

WWTR1 (TAZ), TBX5, and PCAF form a complex

Stable Identifier

R-HSA-2032794

Type

Reaction [binding]

Species

Homo sapiens

Compartment

nucleoplasm

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WWTR1 (TAZ), TBX5, and PCAF form a complex

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In the nucleus the WWTR1 (TAZ) transcriptional coactivator can bind the TBX5 transcription factor and PCAF (KAT2B) histone acetyltransferase to form a complex. The stoichiometry of this complex is unknown (Murakami et al. 2005).

Literature References

PubMed ID	Title	Journal	Year
16332960	A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome Murakami, M, Olson, EN, Nakagawa, O, Nakagawa, M	Proc Natl Acad Sci U S A	2005