Elongation of docosatetraenoyl-CoA to tetracosatetraenoyl-CoA

Stable Identifier
R-HSA-2046095
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
SVG |   | PPTX  | SBGN
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Docosatetraenoyl-CoA is elongated to tetracosatetraenoyl-CoA (TTA-CoA, 9,12,15,18-tetracosatetraenoic acid, 9,12,15,18-24:4(n-6)) by the elongase enzyme ELOVL2.
Literature References
PubMed ID Title Journal Year
9704073 Fate of linoleic, arachidonic, and docosa-7,10,13,16-tetraenoic acids in rat testicles

Ayala, S, Peluffo, RO, Kunau, W, Brenner, RR, Gaspar, G

J Lipid Res 1973
14636670 Elongation of long-chain fatty acids

Huang, YS, Sprecher, H, Pereira, SL, Leonard, AE

Prog Lipid Res 2004
5411545 The biosynthesis of delta-9,12,15,18-tetracosatetraenoic and of delta-6,9,12,15,18-tetracosapentaenoic acids by rat testes

Bridges, RB, Coniglio, JG

J Biol Chem 1970
Participants
Participates
Catalyst Activity

fatty acid elongase activity of ELOVL2 [endoplasmic reticulum membrane]

Orthologous Events
Authored
Created
Cite Us!