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DOHH [cytosol]
Stable Identifier
R-HSA-204619
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Deoxyhypusine hydroxylase apoenzyme, DOHH apoenzyme
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Homo sapiens)
Hypusine synthesis from eIF5A-lysine (Homo sapiens)
DOHH:Fe2+ hydroxylates Dhp-K50-EIF5A to form Hyp-K50-EIF5A (Homo sapiens)
DOHH:Fe++ [cytosol] (Homo sapiens)
DOHH [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BU89 DOHH
Gene Names
DOHH, HLRC1
Chain
chain:1-302
Reference Genes
BioGPS Gene:83475 DOHH
COSMIC (genes):DOHH DOHH
CTD Gene:83475 DOHH
dbSNP Gene:83475 DOHH
ENSEMBL:ENSG00000129932 DOHH
ENSEMBL_homo_sapiens_GENE:ENSG00000129932.10 DOHH
HGNC:28662 DOHH
KEGG Gene (Homo sapiens):83475 DOHH
Monarch:83475 DOHH
NCBI Gene:83475 DOHH
OMIM:611262 DOHH
UCSC:Q9BU89 DOHH
Reference Transcript
RefSeq:NM_031304.4 DOHH
RefSeq:NM_001145165.1 DOHH
Other Identifiers
11729788_at
11729789_at
16867064
208141_PM_s_at
208141_s_at
33176_at
3846215
3846216
3846217
3846218
3846220
3846222
3846223
3846224
3846225
8032595
83475
GE83229
GO:0003824
GO:0004497
GO:0005506
GO:0005515
GO:0005575
GO:0005829
GO:0008612
GO:0016491
GO:0019135
GO:0036211
GO:0046872
GO:0051604
GO:0140096
HMNXSV003034328
ILMN_1784977
PH_hs_0005068
TC19001043.hg
g13775227_3p_s_at
Participates
as a component of
DOHH:Fe++ [cytosol] (Homo sapiens)
Inferred To
DOHH [cytosol]
(Bos taurus)
DOHH [cytosol]
(Caenorhabditis elegans)
DOHH [cytosol]
(Canis familiaris)
DOHH [cytosol]
(Danio rerio)
DOHH [cytosol]
(Dictyostelium discoideum)
DOHH [cytosol]
(Drosophila melanogaster)
DOHH [cytosol]
(Gallus gallus)
DOHH [cytosol]
(Mus musculus)
DOHH [cytosol]
(Plasmodium falciparum)
DOHH [cytosol]
(Rattus norvegicus)
DOHH [cytosol]
(Saccharomyces cerevisiae)
DOHH [cytosol]
(Schizosaccharomyces pombe)
DOHH [cytosol]
(Sus scrofa)
DOHH [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_112594.1
,
NP_001138637.1
OpenTargets
ENSG00000129932
HPA
ENSG00000129932-DOHH
GeneCards
Q9BU89
Ensembl
ENST00000427575
,
ENST00000672935
,
ENSP00000398882
,
ENSG00000129932
,
ENSP00000500806
PRO
Q9BU89
Pharos - Targets
Q9BU89
HMDB Protein
HMDBP09193
PDB
4D4Z
,
4D50
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9NQZ5 STARD7
3
pre-STARD7 [mitochondrial intermembrane space]
(R-HSA-9839780)
cytosolic STARD7 [mitochondrial outer membrane]
(R-HSA-9856506)
mito-STARD7 [mitochondrial outer membrane]
(R-HSA-8873841)
0.527
2
UniProt:Q9HA64 FN3KRP
1
FN3KRP [cytosol]
(R-HSA-6788875)
0.527
2
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