Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
BTRC:CUL1:RBX1:SKP1 [cytosol]
Stable Identifier
R-HSA-206748
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Synonyms
SCF beta-TrCP complex, beta-TrCP:Skp1:Cul1:Rbx1
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Cytokine Signaling in Immune system (Homo sapiens)
Prolactin receptor signaling (Homo sapiens)
PRLR binds SCF beta-TrCP complex (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
Prolactin receptor is internalized (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
Prolactin receptor ligands bind the prolactin receptor (Homo sapiens)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
Signaling by Interleukins (Homo sapiens)
Interleukin-1 family signaling (Homo sapiens)
Interleukin-1 signaling (Homo sapiens)
Beta-TrCP ubiquitinates NFKB p50:p65:phospho IKBA complex (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
BTRC:CUL1:RBX1:SKP1:NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA:BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA:BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Hedgehog (Homo sapiens)
Hedgehog 'off' state (Homo sapiens)
Degradation of GLI1 by the proteasome (Homo sapiens)
SCF(beta-TrCP) ubiquitinates p-GLI1 (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
Degradation of GLI2 by the proteasome (Homo sapiens)
SCF(beta-TrCP) ubiquitinates p-GLI2 (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
GLI3 is processed to GLI3R by the proteasome (Homo sapiens)
SCF(beta-TrCP) ubiquitinates p-GLI3 (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
Signaling by WNT (Homo sapiens)
Degradation of beta-catenin by the destruction complex (Homo sapiens)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
Degradation of ubiquitinated beta catenin by the proteasome (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Homo sapiens)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
Multi-ubiquitination of phospho-beta-catenin by RBX1:SCF(beta-TrCP1) (Homo sapiens)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
ubiquitinated phospho-beta-catenin:RBX1:SCF(beta-TrCP1) complex [cytosol] (Homo sapiens)
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Homo sapiens)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
Participants
components
BTRC [cytosol]
(Homo sapiens)
CUL1 [cytosol]
(Homo sapiens)
RBX1 [cytosol]
(Homo sapiens)
SKP1 [cytosol]
(Homo sapiens)
Participates
as an output of
Prolactin receptor is internalized (Homo sapiens)
Degradation of ubiquitinated beta catenin by the proteasome (Homo sapiens)
as an input of
PRLR binds SCF beta-TrCP complex (Homo sapiens)
Association of beta-catenin with the RBX1:SCF(beta-TrCP1) ubiquitin ligase complex (Homo sapiens)
SCF Beta-TrCP complex binds to NFKB p50:p65: phospho IKBA complex (Homo sapiens)
as a component of
RBX1:SKP1:CUL1:beta-TrCP1:phosphorylated beta-catenin complex [cytosol] (Homo sapiens)
PRLR ligands:p-S349- PRLR:JAK2 dimer:SCF beta-TrCP complex [plasma membrane] (Homo sapiens)
BTRC:CUL1:RBX1:SKP1:NFKB1:RELA:p-S32,S36-NFKBIA:Ub [cytosol] (Homo sapiens)
NFKB1(1-433):RELA:p-S32,S36-NFKBIA:BTRC:CUL1:RBX1:SKP1 [cytosol] (Homo sapiens)
Inferred To
BTRC:CUL1:RBX1:SKP1 [cytosol]
(Bos taurus)
BTRC:CUL1:RBX1:SKP1 [cytosol]
(Caenorhabditis elegans)
BTRC:CUL1:RBX1:SKP1 [cytosol]
(Canis familiaris)
BTRC:CUL1:RBX1:SKP1 [cytosol]
(Danio rerio)
BTRC:CUL1:RBX1:SKP1 [cytosol]
(Dictyostelium discoideum)
BTRC:CUL1:RBX1:SKP1 [cytosol]
(Drosophila melanogaster)
BTRC:CUL1:RBX1:SKP1 [cytosol]
(Gallus gallus)
BTRC:CUL1:RBX1:SKP1 [cytosol]
(Mus musculus)
BTRC:CUL1:RBX1:SKP1 [cytosol]
(Plasmodium falciparum)
BTRC:CUL1:RBX1:SKP1 [cytosol]
(Rattus norvegicus)
BTRC:CUL1:RBX1:SKP1 [cytosol]
(Saccharomyces cerevisiae)
BTRC:CUL1:RBX1:SKP1 [cytosol]
(Schizosaccharomyces pombe)
BTRC:CUL1:RBX1:SKP1 [cytosol]
(Sus scrofa)
BTRC:CUL1:RBX1:SKP1 [cytosol]
(Xenopus tropicalis)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text