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Heparan(2)-PGs [Golgi lumen]
Stable Identifier
R-HSA-2076412
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
Golgi lumen
Locations in the PathwayBrowser
Expand all
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of glycosylation (Homo sapiens)
Diseases associated with glycosaminoglycan metabolism (Homo sapiens)
Defective EXT1 causes exostoses 1, TRPS2 and CHDS (Homo sapiens)
Defective EXT1 (in EXT1:EXT2) does not transfer GlcA to heparan (Homo sapiens)
Heparan(2)-PGs [Golgi lumen] (Homo sapiens)
Defective EXT2 causes exostoses 2 (Homo sapiens)
Defective EXT2 (in EXT1:EXT2) does not transfer GlcA to heparan (Homo sapiens)
Heparan(2)-PGs [Golgi lumen] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of carbohydrates (Homo sapiens)
Glycosaminoglycan metabolism (Homo sapiens)
Heparan sulfate/heparin (HS-GAG) metabolism (Homo sapiens)
HS-GAG biosynthesis (Homo sapiens)
EXT1:EXT2 transfer GlcNAc to the heparan chain (Homo sapiens)
Heparan(2)-PGs [Golgi lumen] (Homo sapiens)
EXT1:EXT2 transfers GlcA to heparan (Homo sapiens)
Heparan(2)-PGs [Golgi lumen] (Homo sapiens)
Participants
members
Heparan(2)-AGRN [Golgi lumen]
(Homo sapiens)
Heparan(2)-GPC1 [Golgi lumen]
(Homo sapiens)
Heparan(2)-GPC2 [Golgi lumen]
(Homo sapiens)
Heparan(2)-GPC3 [Golgi lumen]
(Homo sapiens)
Heparan(2)-GPC4 [Golgi lumen]
(Homo sapiens)
Heparan(2)-GPC5 [Golgi lumen]
(Homo sapiens)
Heparan(2)-GPC6 [Golgi lumen]
(Homo sapiens)
Heparan(2)-HSPG2 [Golgi lumen]
(Homo sapiens)
Heparan(2)-SDC1 [Golgi lumen]
(Homo sapiens)
Heparan(2)-SDC2 [Golgi lumen]
(Homo sapiens)
Heparan(2)-SDC3 [Golgi lumen]
(Homo sapiens)
Heparan(2)-SDC4 [Golgi lumen]
(Homo sapiens)
Participates
as an input of
Defective EXT2 (in EXT1:EXT2) does not transfer GlcA to heparan (Homo sapiens)
Defective EXT1 (in EXT1:EXT2) does not transfer GlcA to heparan (Homo sapiens)
EXT1:EXT2 transfers GlcA to heparan (Homo sapiens)
as an output of
EXT1:EXT2 transfer GlcNAc to the heparan chain (Homo sapiens)
Inferred To
Heparan(2)-PGs [Golgi lumen]
(Bos taurus)
Heparan(2)-PGs [Golgi lumen]
(Caenorhabditis elegans)
Heparan(2)-PGs [Golgi lumen]
(Canis familiaris)
Heparan(2)-PGs [Golgi lumen]
(Danio rerio)
Heparan(2)-PGs [Golgi lumen]
(Drosophila melanogaster)
Heparan(2)-PGs [Golgi lumen]
(Gallus gallus)
Heparan(2)-PGs [Golgi lumen]
(Mus musculus)
Heparan(2)-PGs [Golgi lumen]
(Rattus norvegicus)
Heparan(2)-PGs [Golgi lumen]
(Sus scrofa)
Heparan(2)-PGs [Golgi lumen]
(Xenopus tropicalis)
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