Reactome | 25(OH)D binds GC

25(OH)D binds GC

Stable Identifier

R-HSA-209944

Type

Reaction [transition]

Species

Homo sapiens

Compartment

extracellular region

ReviewStatus

5/5

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Vitamin D binding protein (GC aka DBP), a plasma protein, carries vitamin D metabolites in the circulation. 25-hydroxyvitamin D (25(OH)D) translocates to the extracellular region where it binds with GC and is transported to the kidney (Verboven et al. 2002).

Literature References

PubMed ID	Title	Journal	Year
11799400	A structural basis for the unique binding features of the human vitamin D-binding protein Verboven, C, Rabijns, A, De Maeyer, M, Van Baelen, H, Bouillon, R, De Ranter, C	Nat Struct Biol	2002