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RIMS1 [cytosol]
Stable Identifier
R-HSA-210407
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
RIM (Rab3A interacting)
Locations in the PathwayBrowser for interactor UniProt:Q9UKM9 RALY
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter release cycle (Homo sapiens)
GABA synthesis, release, reuptake and degradation (Homo sapiens)
GABA loaded synaptic vesicle Docking and Priming (Homo sapiens)
RIMS1 [cytosol] (Homo sapiens)
Release of GABA at the synapse (Homo sapiens)
RIMS1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q86UR5 RIMS1
Gene Names
RIMS1, KIAA0340, RAB3IP2, RIM1, Nbla00761
Chain
chain:1-1692
Reference Genes
BioGPS Gene:22999 RIMS1
COSMIC (genes):RIMS1 RIMS1
CTD Gene:22999 RIMS1
dbSNP Gene:22999 RIMS1
ENSEMBL:ENSG00000079841 RIMS1
ENSEMBL_homo_sapiens_GENE:ENSG00000079841.20 RIMS1
HGNC:17282 RIMS1
KEGG Gene (Homo sapiens):22999 RIMS1
Monarch:22999 RIMS1
NCBI Gene:22999 RIMS1
OMIM:606629 RIMS1
UCSC:Q86UR5 RIMS1
Reference Transcript
RefSeq:NM_001168409.1 RIMS1
RefSeq:XM_011535615.2 RIMS1
RefSeq:NM_001168410.1 RIMS1
RefSeq:NM_001168411.1 RIMS1
RefSeq:NM_001168407.1 RIMS1
RefSeq:NM_001168408.1 RIMS1
RefSeq:NM_014989.5 RIMS1
Other Identifiers
11732625_a_at
11748093_x_at
11748173_a_at
11749007_a_at
11749008_x_at
11751189_x_at
17010198
216184_PM_s_at
216184_s_at
22999
231986_PM_at
231986_at
2913124
2913125
2913126
2913127
2913128
2913142
2913154
2913160
2913161
2913162
2913163
2913164
2913165
2913169
2913170
2913171
2913174
2913175
2913176
2913178
2913179
2913180
2913181
2913182
2913183
2913184
2913186
2913187
2913188
2913189
2913194
2913195
2913196
2913197
2913202
2913203
2913204
2913207
2913209
2913210
2913212
2913218
2913221
2913225
2913226
2913227
2913229
2913231
2913233
2913234
2913235
2913236
2913237
2913238
2913239
2913240
2913241
2913242
45152_at
8120613
A_14_P112260
A_14_P135151
A_23_P432110
A_33_P3218832
GE56128
GO:0003723
GO:0005515
GO:0005829
GO:0005856
GO:0005886
GO:0006836
GO:0006886
GO:0006887
GO:0007601
GO:0010628
GO:0016020
GO:0016079
GO:0016192
GO:0017156
GO:0022414
GO:0023052
GO:0030154
GO:0030695
GO:0031267
GO:0042391
GO:0042734
GO:0042995
GO:0043226
GO:0044325
GO:0045055
GO:0045202
GO:0046872
GO:0046903
GO:0046928
GO:0048167
GO:0048786
GO:0048788
GO:0048791
GO:0048856
GO:0050806
GO:0050877
GO:0050896
GO:0060478
GO:0061024
GO:0061025
GO:0065003
GO:0097151
GO:0098772
GO:1903861
GO:2000300
GO:2000463
HMNXSV003017660
HMNXSV003035093
Hs.129190.0.S1_3p_at
Hs.306955.0.S1_3p_s_at
ILMN_1700759
TC06000726.hg
Participates
as an input of
GABA loaded synaptic vesicle Docking and Priming (Homo sapiens)
as an output of
Release of GABA at the synapse (Homo sapiens)
as a component of
Docked GABA loaded synaptic vesicle [cytosol] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
Inferred To
RIMS1 [cytosol]
(Bos taurus)
RIMS1 [cytosol]
(Caenorhabditis elegans)
RIMS1 [cytosol]
(Canis familiaris)
RIMS1 [cytosol]
(Mus musculus)
RIMS1 [cytosol]
(Rattus norvegicus)
RIMS1 [cytosol]
(Sus scrofa)
Ghost homologue of RIMS1 [cytosol]
(Gallus gallus)
rims1 [cytosol]
(Xenopus tropicalis)
Rim [cytosol]
(Drosophila melanogaster)
Cross References
RefSeq
NP_001161879.1
,
NP_001161883.1
,
NP_001161880.1
,
XP_011533917.2
,
NP_001161882.1
,
NP_055804.2
,
NP_001161881.1
OpenTargets
ENSG00000079841
HPA
ENSG00000079841-RIMS1
GeneCards
Q86UR5
Ensembl
ENSP00000430932
,
ENST00000491071
,
ENSP00000428417
,
ENSP00000264839
,
ENST00000401910
,
ENST00000414192
,
ENST00000425662
,
ENST00000264839
,
ENST00000520567
,
ENST00000521978
,
ENST00000518273
,
ENST00000517960
,
ENST00000523963
,
ENSP00000430408
,
ENSP00000430502
,
ENSP00000430101
,
ENSG00000079841
,
ENSP00000385649
,
ENSP00000411235
,
ENST00000517827
,
ENSP00000402273
,
ENSP00000428328
,
ENSP00000428367
,
ENSP00000429959
,
ENST00000522291
PRO
Q86UR5
Pharos - Targets
Q86UR5
Orphanet
15212
HMDB Protein
HMDBP07972
PDB
2CSS
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P06241 FYN
6
p-S21,Y420-FYN [cytosol]
(R-HSA-5218745)
p-Y531-FYN [cytosol]
(R-HSA-391819)
MyrG2-PalmC3,6-FYN [plasma membrane]
(R-HSA-9606873)
p-Y420-FYN [cytosol]
(R-HSA-391821)
MyrG-p-Y420-FYN [plasma membrane]
(R-HSA-1810410)
FYN [cytosol]
(R-HSA-200917)
0.564
2
UniProt:Q9UJD0 RIMS3
0.527
3
UniProt:P27448 MARK3
1
MARK3 [cytosol]
(R-HSA-5672591)
0.499
3
UniProt:P51114 FXR1
2
FXR1(2-784)-BRAF(381-766) fusion [cytosol]
(R-HSA-6802326)
FXR1(2-784)-p-BRAF(381-766) fusion [cytosol]
(R-HSA-6802530)
0.499
2
UniProt:Q9UKM9 RALY
0.499
2
UniProt:O75899 GABBR2
1
GABBR2 [plasma membrane]
(R-HSA-420747)
0.499
2
UniProt:P78362 SRPK2
1
SRPK2 [cytosol]
(R-HSA-9729332)
0.499
3
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