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UNC13B [cytosol]
Stable Identifier
R-HSA-210475
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Munc 13
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter release cycle (Homo sapiens)
Acetylcholine Neurotransmitter Release Cycle (Homo sapiens)
Acetylcholine synaptic vesicle docking and priming (Homo sapiens)
Docked acetylcholine loaded Synaptic Vesicle [plasma membrane] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
Release of acetylcholine at the synapse (Homo sapiens)
Docked acetylcholine loaded Synaptic Vesicle [plasma membrane] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
Dopamine Neurotransmitter Release Cycle (Homo sapiens)
Dopamine synaptic vesicle docking and priming (Homo sapiens)
Docked dopamine loaded synaptic vesicle [plasma membrane] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
Release of docked dopamine loaded synaptic vesicle (Homo sapiens)
Docked dopamine loaded synaptic vesicle [plasma membrane] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
Glutamate Neurotransmitter Release Cycle (Homo sapiens)
Glutamate synaptic vesicle docking and priming (Homo sapiens)
Docked Glutamate Loaded Synaptic Vesicle [plasma membrane] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
Release of L-Glutamate at the synapse (Homo sapiens)
Docked Glutamate Loaded Synaptic Vesicle [plasma membrane] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
Norepinephrine Neurotransmitter Release Cycle (Homo sapiens)
Noradrenalin synaptic vesicle docking and priming (Homo sapiens)
Docked Noradrenalin loaded synaptic vesicle [plasma membrane] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
Release of noradrenaline at the synapse (Homo sapiens)
Docked Noradrenalin loaded synaptic vesicle [plasma membrane] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
Serotonin Neurotransmitter Release Cycle (Homo sapiens)
Release of docked serotonin loaded synaptic vesicle (Homo sapiens)
Docked serotonin loaded synaptic vesicle [plasma membrane] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
Serotonin loaded synaptic vesicle docking and priming (Homo sapiens)
Docked serotonin loaded synaptic vesicle [plasma membrane] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
UNC13B [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:O14795 UNC13B
Gene Names
UNC13B, UNC13
Chain
chain:1-1591
Reference Genes
BioGPS Gene:10497 UNC13B
COSMIC (genes):UNC13B UNC13B
CTD Gene:10497 UNC13B
dbSNP Gene:10497 UNC13B
ENSEMBL:ENSG00000198722 UNC13B
HGNC:12566 UNC13B
KEGG:hsa:10497 UNC13B
Monarch:10497 UNC13B
NCBI Gene:10497 UNC13B
OMIM:605836 UNC13B
UCSC:O14795 UNC13B
Reference Transcript
RefSeq:NM_006377.3 UNC13B
RefSeq:NM_001330653.1 UNC13B
Other Identifiers
10497
11717679_a_at
11717680_at
11748231_a_at
11752450_a_at
17084605
202893_PM_at
202893_at
3167732
3167733
3167734
3167735
3167740
3167741
3167744
3167745
3167746
3167748
3167750
3167757
3167758
3167761
3167762
3167763
3167764
3167765
3167766
3167767
3167768
3167769
3167770
3167771
3167773
3167774
3167775
3167776
3167778
3167779
3167780
3167781
3167782
3167783
3167784
3167785
3167786
3167787
3167788
3167789
3167791
3167793
3167798
3167799
3167800
3167801
3167802
3167803
3167804
3167805
3167806
3167807
3167808
3167811
3167812
3167813
3167814
3167815
3167816
3167817
3167818
3167819
3167820
3167821
3167822
3167823
3167824
3167825
3167826
3167827
3167828
3167829
3167852
40087_at
8154981
A_14_P123722
A_23_P253395
A_33_P3318926
GE54160
GO:0005509
GO:0005515
GO:0005516
GO:0005543
GO:0005737
GO:0005794
GO:0005829
GO:0005886
GO:0006887
GO:0007268
GO:0008289
GO:0010808
GO:0016020
GO:0016081
GO:0016082
GO:0016192
GO:0017075
GO:0019992
GO:0023052
GO:0030672
GO:0030742
GO:0031267
GO:0031594
GO:0035249
GO:0042734
GO:0043065
GO:0043195
GO:0043226
GO:0045202
GO:0046872
GO:0048786
GO:0050714
GO:0060478
GO:0061789
GO:0065003
GO:0071333
GO:0097151
GO:0098793
GO:0098831
GO:0099011
GO:0099525
HMNXSV003036841
ILMN_1669747
PH_hs_0029248
TC09000182.hg
g5454147_3p_at
Participates
as a component of
RIMS1:UNC13B:BZRAP1:Alpha-liprin [plasma membrane] (Homo sapiens)
This entity regulates
Positively
Glutamate synaptic vesicle docking and priming
(Homo sapiens)
Inferred To
Ghost homologue of UNC13B [cytosol]
(Xenopus tropicalis)
UNC13B [cytosol]
(Bos taurus)
UNC13B [cytosol]
(Caenorhabditis elegans)
UNC13B [cytosol]
(Canis familiaris)
UNC13B [cytosol]
(Gallus gallus)
UNC13B [cytosol]
(Mus musculus)
UNC13B [cytosol]
(Rattus norvegicus)
UNC13B [cytosol]
(Sus scrofa)
unc-13 [cytosol]
(Drosophila melanogaster)
Cross References
RefSeq
NP_006368.3
,
NP_001317582.1
ENSEMBL
ENSP00000367756
,
ENST00000619578
,
ENST00000378495
,
ENSP00000479261
OpenTargets
ENSG00000198722
HPA
ENSG00000198722-UNC13B
PRO
O14795
Pharos - Targets
O14795
GlyGen
O14795
HMDB Protein
HMDBP08095
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96HU8 DIRA2
0.527
2
UniProt:O95057 DIRA1
0.499
2
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