Reactome | CACNG8 [plasma membrane]

CACNG8 [plasma membrane]

Stable Identifier

R-HSA-210486

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Gamma 8 subunit of VGCC, stargazin

Locations in the PathwayBrowser

Expand all

Developmental Biology (Homo sapiens)

- LGI-ADAM interactions (Homo sapiens)
  - LGI1 binds ADAM22 and ADAM23 (Homo sapiens)
    - ADAM22:LGI1 dimer:ADAM23 [plasma membrane] (Homo sapiens)
      - ADAM22:PSD-95:stargazin [plasma membrane] (Homo sapiens)
        
        Gamma subunit of VGCC (Stargazin) [plasma membrane] (Homo sapiens)
        
        CACNG8 [plasma membrane] (Homo sapiens)
    - ADAM22:PSD-95:stargazin [plasma membrane] (Homo sapiens)
      - Gamma subunit of VGCC (Stargazin) [plasma membrane] (Homo sapiens)
        
        CACNG8 [plasma membrane] (Homo sapiens)

Neuronal System (Homo sapiens)

- Transmission across Chemical Synapses (Homo sapiens)
  - Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
    - Glutamate binding, activation of AMPA receptors and synaptic plasticity (Homo sapiens)
      - Trafficking of AMPA receptors (Homo sapiens)
        
        Trafficking of GluR1-containing AMPA receptors (Homo sapiens)
        
        TARP-PSD95-Mdm2 [plasma membrane] (Homo sapiens)
        
        Gamma subunit of VGCC (Stargazin) [plasma membrane] (Homo sapiens)
        
        CACNG8 [plasma membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q8WXS5 CACNG8

Gene Names

CACNG8, CACNG6

Chain

chain:1-425

Reference Genes

BioGPS Gene:59283 CACNG8

COSMIC (genes):CACNG8 CACNG8

CTD Gene:59283 CACNG8

dbSNP Gene:59283 CACNG8

ENSEMBL:ENSG00000142408 CACNG8

ENSEMBL_homo_sapiens_GENE:ENSG00000142408.7 CACNG8

HGNC:13628 CACNG8

KEGG Gene (Homo sapiens):59283 CACNG8

Monarch:59283 CACNG8

NCBI Gene:59283 CACNG8

OMIM:606900 CACNG8

UCSC:Q8WXS5 CACNG8

Reference Transcript

RefSeq:NM_031895.5 CACNG8

Other Identifiers

11715124_s_at

16865162

17125822

231355_PM_at

231355_at

234756_3p_at

234756_PM_at

234756_at

3841158

3841159

3841160

3841162

3841163

3841164

3841165

3841166

3841167

3841168

3841169

3841170

3841171

3841173

3841175

3841177

3841179

3841181

3841182

3841183

3841185

3841186

3841187

3841188

3841189

44582_at

59283

8031084

A_23_P420218

A_32_P61693

GE61253

GE619241

GE766119

GO:0005215

GO:0005245

GO:0005246

GO:0005262

GO:0005886

GO:0005891

GO:0006811

GO:0006816

GO:0006886

GO:0014069

GO:0016020

GO:0016192

GO:0016247

GO:0019226

GO:0023052

GO:0030666

GO:0031410

GO:0032281

GO:0034220

GO:0034702

GO:0043226

GO:0045202

GO:0045211

GO:0050877

GO:0051968

GO:0055085

GO:0070588

GO:0098772

GO:0098839

GO:0098943

GO:0098970

GO:0099590

GO:1990454

GO:2000311

HMNXSV003009443

HMNXSV003058323

Hs.31833.0.A1_3p_at

Hs.326762.0.S1_3p_at

Hs.326762.0.S1_3p_x_at

ILMN_1776079

ILMN_2106874

PH_hs_0028172

TC19000869.hg

TC19002229.hg

TC19002230.hg

Participates

as a member of

Other forms of this molecule

CACNG8 [endocytic vesicle membrane]

Inferred To

CACNG8 [plasma membrane] (Bos taurus)

CACNG8 [plasma membrane] (Canis familiaris)

CACNG8 [plasma membrane] (Sus scrofa)

Homologues of CACNG8 [plasma membrane] (Caenorhabditis elegans)

stg-2 [plasma membrane] (Caenorhabditis elegans)

Cacng8 [plasma membrane] (Mus musculus)

Cacng8 [plasma membrane] (Rattus norvegicus)

stg-1 [plasma membrane] (Caenorhabditis elegans)

stg1 [plasma membrane] (Drosophila melanogaster)

Cross References

RefSeq

NP_114101.4

OpenTargets

ENSG00000142408

HPA

ENSG00000142408-CACNG8

GeneCards

Q8WXS5

Ensembl

ENSP00000270458, ENSG00000142408, ENST00000270458

PRO

Q8WXS5

Pharos - Targets

Q8WXS5

HMDB Protein

HMDBP07568