NEUROG3-dependent synthesis of INSM1

Stable Identifier
R-HSA-210913
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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NEUROG3-dependent synthesis of INSM1
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The INSM1 gene is transcribed, its mRNA is translated, and the protein product is transported to the nucleus. INSM1 transcription requires the activity of the NEUROG3 transcription factor (Mellitzer et al. 2006).
Literature References
PubMed ID Title Journal Year
16511571 IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas

Mellitzer, G, Lan, M, Mansouri, A, Lee, J, Lenne-Samuel, N, Luco, RF, Gradwohl, G, Bonne, S, Van De Casteele, M, Ferrer, J, Collombat, P, Pipeleers, D, Heimberg, H, Nielsen, FC

EMBO J 2006
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
NEUROG3 [nucleoplasm] (Homo sapiens)
Authored
Tello-Ruiz, MK  (2008-05-24)
Ferrer, J  (2008-05-24)
Reviewed
Jensen, J  (2008-05-13)
Created
D'Eustachio, P  (2008-01-18)
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