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Go!
PDX1 [nucleoplasm]
Stable Identifier
R-HSA-211179
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
IPF1
Icon
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Regulation of beta-cell development (Homo sapiens)
Regulation of gene expression in beta cells (Homo sapiens)
FOXOA2-, MAFA-, and PAX6-dependent synthesis of PDX1 protein (Homo sapiens)
PDX1 [nucleoplasm] (Homo sapiens)
MAFA-, NKX2-2-, PAX6-, and PDX1-dependent synthesis of insulin precursor protein (Homo sapiens)
PDX1 [nucleoplasm] (Homo sapiens)
NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein (Homo sapiens)
PDX1 [nucleoplasm] (Homo sapiens)
PDX1-dependent synthesis of IAPP protein (Homo sapiens)
PDX1 [nucleoplasm] (Homo sapiens)
PDX1-dependent synthesis of NKX6-1 protein (Homo sapiens)
PDX1 [nucleoplasm] (Homo sapiens)
Regulation of gene expression in early pancreatic precursor cells (Homo sapiens)
HNF6- and FGF10-dependent synthesis of PDX1 protein (Homo sapiens)
PDX1 [nucleoplasm] (Homo sapiens)
PDX1-dependent synthesis of NKX6-1 protein (Homo sapiens)
PDX1 [nucleoplasm] (Homo sapiens)
PDX1-dependent synthesis of NR5A2 protein (Homo sapiens)
PDX1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P52945 PDX1
Gene Names
PDX1, IPF1, STF1
Chain
chain:1-283
Reference Genes
BioGPS Gene:3651 PDX1
COSMIC (genes):PDX1 PDX1
CTD Gene:3651 PDX1
dbSNP Gene:3651 PDX1
ENSEMBL:ENSG00000139515 PDX1
ENSEMBL_homo_sapiens_GENE:ENSG00000139515.6 PDX1
HGNC:6107 PDX1
KEGG Gene (Homo sapiens):3651 PDX1
Monarch:3651 PDX1
NCBI Gene:3651 PDX1
OMIM:600733 PDX1
UCSC:P52945 PDX1
Reference Transcript
RefSeq:NM_000209.3 PDX1
Other Identifiers
11741835_at
11758256_s_at
16773547
210937_PM_s_at
210937_s_at
210938_PM_at
210938_at
3483094
3483095
3483096
3483103
3483104
3483105
3483106
3483107
3483108
3483109
3483110
3483111
3651
400_at
71502_at
7968265
A_14_P134042
A_23_P65189
GE476730
GO:0000122
GO:0000785
GO:0000978
GO:0000981
GO:0001889
GO:0003309
GO:0003677
GO:0003682
GO:0003700
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005829
GO:0005975
GO:0006006
GO:0006091
GO:0006351
GO:0006355
GO:0006357
GO:0006366
GO:0007224
GO:0007263
GO:0008283
GO:0008284
GO:0008285
GO:0009410
GO:0009749
GO:0009887
GO:0010040
GO:0010157
GO:0010255
GO:0010468
GO:0012501
GO:0014070
GO:0016331
GO:0016607
GO:0023052
GO:0030073
GO:0030154
GO:0031016
GO:0031017
GO:0031018
GO:0031100
GO:0031667
GO:0032024
GO:0033273
GO:0033993
GO:0034097
GO:0035094
GO:0035774
GO:0035883
GO:0042127
GO:0042593
GO:0043201
GO:0043226
GO:0043279
GO:0043565
GO:0044342
GO:0044877
GO:0045892
GO:0045893
GO:0045944
GO:0048565
GO:0048856
GO:0048863
GO:0050673
GO:0050680
GO:0051384
GO:0060290
GO:0070059
GO:0070542
GO:0097050
GO:0140110
GO:1902236
GO:1904692
GO:1990837
GO:1990841
GO:2000675
HMNXSV003011194
ILMN_1742993
PH_hs_0002768
TC13000082.hg
X99894_at
g1197837_3p_a_at
g929922_3p_at
Participates
as an output of
HNF6- and FGF10-dependent synthesis of PDX1 protein (Homo sapiens)
FOXOA2-, MAFA-, and PAX6-dependent synthesis of PDX1 protein (Homo sapiens)
This entity regulates
Positively
MAFA-, NKX2-2-, PAX6-, and PDX1-dependent synthesis of insulin precursor protein
(Homo sapiens)
PDX1-dependent synthesis of IAPP protein
(Homo sapiens)
PDX1-dependent synthesis of NKX6-1 protein
(Homo sapiens)
PDX1-dependent synthesis of NKX6-1 protein
(Homo sapiens)
PDX1-dependent synthesis of NR5A2 protein
(Homo sapiens)
NEUROD1- and PDX1-dependent synthesis of glucokinase (GCK) protein
(Homo sapiens)
Cross References
RefSeq
NP_000200.1
OpenTargets
ENSG00000139515
GeneCards
P52945
HPA
ENSG00000139515-PDX1
Ensembl
ENST00000381033
,
ENSG00000139515
,
ENSP00000370421
PRO
P52945
Pharos - Targets
P52945
Orphanet
16634
PDB
7KPK
,
6F8F
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