Cleavage of DFF45 (224) by caspase-3

Stable Identifier
R-HSA-211186
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Caspase-3 cleaves DFF45 between residues 224,225.
Literature References
PubMed ID Title Journal Year
9108473 DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

Liu, X, Slaughter, C, Wang, X, Zou, H

Cell 1997
Participants
Participates
Catalyst Activity

cysteine-type endopeptidase activity of active caspase-3 [nucleoplasm]

Orthologous Events
Authored
Reviewed
Created
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