Proteolytically activated PAK-2p34, but not full-length PAK-2, is degraded rapidly by the proteasome (Jakobi et al., 2003). Here, degradation of PAK-2p34 is described as occurring in the cytosol. However, to date it is not known whether this occurs in the nucleus or in the cytoplasm.
Koeppel, MA, Jakobi, R, McCarthy, CC, Stringer, DK
endopeptidase activity of 26S proteasome [cytosol]
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