Xenobiotics

Stable Identifier
R-HSA-211981
Type
Pathway
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane, endoplasmic reticulum lumen
ReviewStatus
5/5
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Xenobiotics
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Of the 50 microsomal CYPs, 15 act on xenobiotics. They all possess wide substrate specificity to cater for most foreign compounds that find their way into the body.
Literature References
PubMed ID Title Journal Year
15102545 57 varieties: the human cytochromes P450

Lewis, DF

Pharmacogenomics 2004
16584116 Cytochrome P450s and other enzymes in drug metabolism and toxicity

Guengerich, FP

AAPS J 2006
12369887 The cytochrome P450 superfamily: biochemistry, evolution and drug metabolism in humans

Danielson, PB

Curr Drug Metab 2002
Participants
Events
Participates
as an event of
Event Information
Go Biological Process
xenobiotic metabolic process (0006805)
Orthologous Events
Xenobiotics (Bos taurus)
Xenobiotics (Caenorhabditis elegans)
Xenobiotics (Canis familiaris)
Xenobiotics (Danio rerio)
Xenobiotics (Dictyostelium discoideum)
Xenobiotics (Drosophila melanogaster)
Xenobiotics (Gallus gallus)
Xenobiotics (Mus musculus)
Xenobiotics (Rattus norvegicus)
Xenobiotics (Sus scrofa)
Xenobiotics (Xenopus tropicalis)
Authored
Jassal, B  (2008-05-19)
Reviewed
D'Eustachio, P  (2008-05-28)
Created
Jassal, B  (2008-02-08)
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