AcK5,12-HIST1H4A [nucleoplasm]

Stable Identifier
R-HSA-212078
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
Histone H4 (acetylated at K5 and K12)
Locations in the PathwayBrowser
External Reference Information
External Reference
Gene Names
H4C1, H4/A, H4FA, HIST1H4A, H4C2, H4/I, H4FI, HIST1H4B, H4C3, H4/G, H4FG, HIST1H4C, H4C4, H4/B, H4FB, HIST1H4D, H4C5, H4/J, H4FJ, HIST1H4E, H4C6, H4/C, H4FC, HIST1H4F, H4C8, H4/H, H4FH, HIST1H4H, H4C9, H4/M, H4FM, HIST1H4I, H4C11, H4/E, H4FE, HIST1H4J, H4C12, H4/D, H4FD, HIST1H4K, H4C13, H4/K, H4FK, HIST1H4L, H4C14, H4/N, H4F2, H4FN, HIST2H4, HIST2H4A, H4C15, H4/O, H4FO, HIST2H4B, H4C16, H4-16, HIST4H4
Chain
initiator methionine:, chain:2-103
Reference Genes
Other Identifiers
11715116_s_at
11726245_s_at
11726246_x_at
11728049_s_at
11733368_at
11733369_x_at
11735753_at
11735775_at
11735776_x_at
11735942_at
11737314_at
11738060_s_at
11738103_at
11738601_at
11741794_s_at
11742669_s_at
11759221_at
121504
152_f_at
16670377
16692626
16761778
17005560
17005868
17016360
17016383
17016406
17016494
17016506
205967_PM_at
205967_at
206951_PM_at
206951_at
207046_PM_at
207046_at
208046_PM_at
208046_at
208076_at
208180_PM_s_at
208180_s_at
208580_PM_x_at
208580_x_at
214463_PM_x_at
214463_x_at
214516_PM_at
214516_at
214562_PM_at
214562_at
232035_PM_at
232035_at
2357896
2357897
2357898
2357899
2357900
2357901
2357902
2357903
2357904
2357906
2357910
2434056
2434103
2434104
2434105
2434106
2434107
2434108
2434109
2434110
2434111
2434116
2899096
2899097
2899147
2899148
2899149
2899218
2899219
2899244
2899245
2899246
2899247
2899248
2899770
2899771
2900064
2900065
2946210
2946211
2946212
2946213
2946320
2946321
2946377
2946379
2946380
2946382
2946384
2946387
2946388
2946389
2947057
2947058
2947082
2947083
2947084
31521_f_at
31751_f_at
33049_at
34027_f_at
3445648
3445649
3445654
3445655
3445656
3445661
39969_at
50025_at
554313
57785_at
59154_at
762_f_at
7905067
7919627
7961483
8117334
8117368
8117402
8117422
8117537
8117598
8124385
8124413
8124448
8124521
8124534
8180255
8180321
82468_at
8294
8359
8360
8361
8362
8363
8364
8365
8366
8367
8368
8370
ADDON000875.hg
ADDON001483.hg
ADDON002748.hg
ADDON002749.hg
ADDON002750.hg
ADDON002752.hg
ADDON002753.hg
ADDON002754.hg
ADDON002776.hg
ADDON002784.hg
ADDON002794.hg
ADDON002882.hg
A_14_P107645
A_14_P121153
A_14_P137590
A_21_P0014172
A_23_P214487
A_23_P30805
A_23_P30813
A_23_P323685
A_23_P359540
A_23_P388871
A_23_P395374
A_23_P415411
A_23_P431179
A_23_P436281
A_23_P70480
A_24_P166407
A_24_P20873
A_24_P261691
A_33_P3299865
A_33_P3344229
A_33_P3351851
A_33_P3410836
GE499003
GE501244
GE502647
GE506852
GE508495
GE572531
GE57844
GE58304
GE59861
GE79334
GE81299
GE81300
GE86856
GO:0000781
GO:0000786
GO:0002376
GO:0003677
GO:0003723
GO:0005198
GO:0005515
GO:0005576
GO:0005615
GO:0005634
GO:0005654
GO:0005694
GO:0006325
GO:0006334
GO:0016020
GO:0030154
GO:0030527
GO:0032200
GO:0032991
GO:0043226
GO:0043505
GO:0045653
GO:0046982
GO:0048856
GO:0061644
GO:0065003
GO:0070062
HMNXSV003000546
HMNXSV003001014
HMNXSV003002656
HMNXSV003005824
HMNXSV003015566
HMNXSV003016171
HMNXSV003017340
HMNXSV003023270
HMNXSV003027409
HMNXSV003037762
HMNXSV003046538
HMNXSV003054339
HMNXSV003057871
Hs.131957.0.S1_3p_at
Hs.143080.0.S1_3p_at
Hs.93758.1.S1_3p_at
Hs.93758.1.S1_3p_x_at
ILMN_1662359
ILMN_1670033
ILMN_1676580
ILMN_1681542
ILMN_1713436
ILMN_1723111
ILMN_1751120
ILMN_1782329
ILMN_2053992
ILMN_2075334
ILMN_2115340
ILMN_2119320
ILMN_2165369
ILMN_2224990
M16707_rna1_at
M16707_rna1_s_at
PH_hs_0007863
PH_hs_0012922
PH_hs_0013176
PH_hs_0013177
PH_hs_0017043
PH_hs_0027130
PH_hs_0028888
PH_hs_0029036
PH_hs_0029514
PH_hs_0031203
PH_hs_0031792
PH_hs_0032299
PH_hs_0032446
PH_hs_0033270
PH_hs_0034759
PH_hs_0034804
TC01001173.hg
TC01003192.hg
TC06000163.hg
TC06000166.hg
TC06000172.hg
TC06000175.hg
TC06000266.hg
TC06001341.hg
TC06001348.hg
TC06001355.hg
TC06001424.hg
TC06001428.hg
TC06002644.hg
TC12001272.hg
X00038_at
X60486_at
X60487_at
Z80787_at
g11415029_3p_x_at
g4504322_3p_at
g5579462_3p_at
g5579465_3p_at
g5579466_3p_a_at
g5579467_3p_at
Participates
Other forms of this molecule
Inferred To
Modified Residues
Name
N6-acetyl-L-lysine at 6
Coordinate
6
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.
Name
N6-acetyl-L-lysine at 13
Coordinate
13
PsiMod Name
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.
Cross References
OpenTargets
GeneCards
ZINC target
PRO
Pharos - Targets
PDB
4QYD, 5FWE, 7V9C, 8TXV, 6BUZ, 6LAB, 7Y5W, 6KE9, 7LYC, 2LVM, 6M4G, 8SN3, 8SB6, 7Y8R, 7V9S, 3W98, 8SN0, 4YYG, 6T93, 5BNX, 6USJ, 6K1J, 3IJ1, 6Y5D, 7U47, 7U0G, 7NL0, 6KXV, 8OTT, 6JOU, 3AZM, 3JPX, 6R91, 7VZ4, 8U13, 3UVY, 6A5L, 5XF3, 3AZI, 3AZE, 5CPJ, 8DK5, 7PFF, 6VO5, 8B5B, 7YQK, 5B2I, 8H0V, 6J4Z, 8ATF, 5Z30, 6L9H, 4M38, 7X58, 7PFA, 4H9O, 6UPL, 7COW, 3F9Z, 8IEJ, 3W97, 6T7B, 5CPI, 7PF3, 7K5X, 8SMZ, 4QUU, 4H9S, 8OTS, 6A5R, 6MLC, 8OSJ, 7XTI, 7YOZ, 7PFV, 7BY0, 6E0C, 7E8D, 3UVX, 5AV9, 4YYJ, 7V9K, 7PEU, 5JA4, 8EVG, 8GUI, 6T90, 7U51, 3X1S, 7PEY, 7WBX, 5GSU, 8X1C, 6IR9, 5B32, 8EVJ, 7EID, 8HAN, 1ZKK, 6MUO, 8XBU, 7XX6, 5ZGC, 6SEE, 8XBT, 7SCZ, 6M4D, 7CJ0, 7XSX, 7PFE, 6L4A, 5Y0D, 6R94, 8IEG, 8Q3X, 6K1I, 4YYD, 5BNV, 6KVD, 7V96, 8GRQ, 8SMW, 5GXQ, 6LA9, 8HAI, 6R90, 8JND, 4HGA, 3QBY, 7XD1, 7LYB, 5YE4, 7XCR, 8JH3, 3F9Y, 3O36, 8SNA, 7U46, 8OO7, 7XZZ, 7UV9, 8HAM, 7XTD, 7YYH, 8OOS, 7XX5, 7K63, 8X19, 7XSE, 6INQ, 4YYN, 5ZBX, 8SN6, 6UPK, 3NQU, 5B24, 8JLD, 6O1D, 4H9N, 8OL1, 5AY8, 3QZV, 5Z23, 2QQS, 8JL9, 7Y7I, 6J4Y, 5JRG, 8YJM, 8JHG, 4H9R, 4GQB, 4QUT, 3AZL, 5GTC, 8HAH, 7Y61, 7R5R, 7PET, 2KWO, 7XD0, 5AV8, 8SN2, 3AZH, 7PII, 7U50, 7LMM, 7PEX, 5B31, 6SE6, 3NQJ, 7PF2, 7X57, 4YM6, 8J6T, 7Y5V, 7U0J, 6FML, 7PF6, 8SN9, 8JH2, 8SN5, 8YTI, 6A5P, 3AV2, 7BXT, 5XF5, 4YYI, 8H1T, 7V9J, 6R93, 7CIZ, 8RBX, 6YOV, 7EIC, 5Y0C, 7WBW, 3W96, 6T7D, 2RS9, 8TXX, 5GSE, 7PFU, 3AYW, 3WTP, 8UPF, 7JOA, 6J51, 3QZT, 8B5A, 6M44, 8IQG, 6C0W, 3AZK, 2KWN, 6JR1, 7SCY, 7LYA, 3AV1, 6L49, 8EVI, 3AZG, 7JZV, 6T7A, 2CV5, 3UVW, 7PFD, 3X1V, 6X5A, 5YE3, 8SMY, 8OX1, 7V90, 7K61, 8SN1, 5C3I, 7Y5U, 5B0Z, 8J6S, 6LA8, 4YY6, 4YYM, 4H9Q, 6SEG, 7PFX, 6RXS, 4U9W, 8GUK, 7CCR, 6R8Z, 2IG0, 8WG5, 6RNY, 7BWD, 7YRD, 7PEW, 8U14, 6LER, 8AAG, 7K60, 6J4X, 7ZI4, 8SYP, 6A5U, 5AVC, 7D20, 6V92, 7C0M, 7YWX, 7XVM, 8OOP, 4Z5T, 3UW9, 3A6N, 3WKJ, 7WBV, 3F9X, 8HAL, 5GT3, 5KDM, 6M4H, 6SE0, 7LMK, 8SMX, 7PF0, 8OX0, 3AFA, 7U53, 8AV6, 5BO0, 6V2K, 6K1K, 8OSL, 8OFF, 4YM5, 7PF5, 5B40, 2RJE, 8YJF, 7W9V, 7U4D, 8X15, 6A5O, 3CFV, 8EVH, 8GUJ, 6R92, 5AV6, 8HAK, 4YYH, 8IHL, 3X1U, 8SPU, 8JNF, 3WAA, 7VCQ, 7V6Q, 3R45, 3F9W, 6T7C, 7XZY, 7XT7, 7U0I, 2RNY, 8Q3M, 7M98, 6M3V, 8GRM, 8XBW, 7PFT, 8HE5, 5FFW, 7XVL, 6JR0, 6ACP, 6LE9, 3AN2, 8Q3E, 4N4F, 6X59, 6T79, 7XCT, 7PFC, 5XF4, 7A08, 8JHF, 7JO9, 3WA9, 5CPK, 8JLB, 6LA2, 4Z2M, 8OSK, 6J50, 5TEG, 5B2J, 7Y00, 8KB5, 5FA5, 4H9P, 6SEF, 7V1M, 7VA4, 2BQZ, 5AVB, 6R8Y, 8TXW, 7TAN, 6HTS, 8HAG, 7PEV, 8JH4, 3CFS, 7U52, 7DBP, 7CCQ, 8OOA, 8SPS, 8SN4, 8JNE, 8HAJ, 4N3W, 8Q36, 6L9Z, 7XSZ, 7XZX, 7Y60, 8SN8, 5B0Y, 7K5Y, 6R0C, 3QZS, 8HLW, 7D1Z, 5X7X, 4YYK, 8B5C, 7PFW, 8SN7, 3AZJ, 5GT0, 5B33, 5AV5, 8JLA, 3X1T, 3W99, 6HKT, 8IQF, 6J4W, 8TGP, 6XJD, 7PEZ, 3AZF, 6MUP, 7PF4, 8H0W, 3AZN, 6A5T, 6E0P
Interactors (73)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q9Y294 ASF1A  1 0.954 17
 UniProt:P68431 HIST1H3G  20 0.891 7
 UniProt:P04908 H2AC4  13 0.874 12
 UniProt:Q12888 TP53BP1  3 0.87 14
 UniProt:P84243 H3-3A  18 0.861 12
 UniProt:P16104 H2AFX  7 0.848 7
 UniProt:P49450 CENPA  2 0.793 6
 UniProt:Q16576 RBBP7  1 0.793 9
 UniProt:Q9NQR1 KMT5A  1 0.775 6
 UniProt:O14744 PRMT5  3 0.756 6
 UniProt:P49736 MCM2  1 0.748 9
 UniProt:Q9NVP2 ASF1B      0.744 6
 UniProt:Q9UER7 DAXX  13 0.744 7
 UniProt:O75164 KDM4A  2 0.743 7
 UniProt:O60885-1 BRD4      0.739 10
 IntAct:EBI-10097414 FOXP3      0.725 4
 UniProt:Q12888-1 TP53BP1      0.722 3
 UniProt:O14929 HAT1  1 0.704 7
 UniProt:Q71DI3 H3C15  20 0.704 4
 UniProt:Q13547 HDAC1  2 0.688 3
 UniProt:Q92993 KAT5  1 0.683 4
 UniProt:Q16695 H3-4  3 0.676 3
 UniProt:Q12830-4 BPTF      0.675 16
 UniProt:P45973 CBX5  2 0.669 3
 UniProt:Q9Y468 L3MBTL1  1 0.667 4
 UniProt:Q15672 TWIST1  1 0.662 5
 UniProt:Q99873 PRMT1  2 0.623 2
 UniProt:Q582G4 ANM7      0.618 4
 UniProt:Q92793 CREBBP  4 0.618 6
 UniProt:Q9BVI0 PHF20  2 0.618 3
 UniProt:P63104 YWHAZ  2 0.564 3
 UniProt:Q8NCD3 HJURP  1 0.564 3
 UniProt:Q16778 H2BC21  9 0.564 2
 UniProt:P17096 HMGA1  2 0.564 2
 UniProt:Q86UY6-1 NAA40      0.558 3
 UniProt:P55201 BRPF1  1 0.558 8
 UniProt:A8MW92 PHF20L1  1 0.558 2
 UniProt:Q9VK33  2 0.558 10
 UniProt:P49450-1 CENPA      0.558 2
 IntAct:EBI-9077146 7SK      0.558 2
 UniProt:P25440 BRD2  1 0.558 5
 UniProt:P35609 ACTN2  3 0.556 3
 UniProt:Q8TAP4-4 LMO3      0.556 3
 UniProt:P61981 YWHAG  1 0.556 3
 UniProt:Q15047-2 SETDB1      0.556 3
 UniProt:P42858 HTT  1 0.556 3
 UniProt:Q8IUQ4 SIAH1  1 0.556 3
 UniProt:P17252 PRKCA  8 0.556 3
 UniProt:Q05BQ5 MBTD1      0.544 3
 UniProt:O60264 SMARCA5  1 0.544 2
 UniProt:Q14684-1 RRP1B      0.537 3
 UniProt:Q13185 CBX3  1 0.527 2
 UniProt:Q08945 SSRP1  1 0.527 2
 UniProt:Q01831 XPC  5 0.527 3
 UniProt:P49321 NASP      0.527 2
 UniProt:P33993 MCM7  1 0.527 3
 UniProt:Q92731 ESR2  5 0.527 5
 UniProt:P33991 MCM4  1 0.527 3
 UniProt:P0C0S8 H2AC11  11 0.527 2
 UniProt:P0C0S5 H2AZ1  1 0.527 3
 UniProt:Q9UER7-1 DAXX      0.527 9
 UniProt:Q13112 CAF1B      0.527 2
 UniProt:Q14566 MCM6  1 0.527 3
 UniProt:P83916 CBX1  1 0.527 2
 UniProt:P62993 GRB2  1 0.527 2
 UniProt:Q9NQ92 COPRS  1 0.525 3
 UniProt:P33992 MCM5  1 0.499 2
 UniProt:Q09028 RBBP4  1 0.499 2
 UniProt:P25205 MCM3  1 0.499 2
 UniProt:C4QZQ7 C4QZQ7      0.495 2
 UniProt:P13569 CFTR  17 0.483 11
 UniProt:P0DTC4 E  9 0.482 2
 UniProt:Q9UHJ3 SMBT1      0.462 2
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