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Histone H3 (H3K27me3) [nucleoplasm]
Stable Identifier
R-HSA-212266
Type
Set [DefinedSet]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular Senescence (Homo sapiens)
Oxidative Stress Induced Senescence (Homo sapiens)
Demethylation of H3K27Me3 by KDM6B stimulates p16INK4A transcription, while binding of PRC1.4 complex to H3K27Me3 represses p16INK4A transcription (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
KDM6B demethylates H3K27me3 on p16INK4A promoter (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
p-MAPKAPK3 phosphorylates BMI1 (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] (Homo sapiens)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
Developmental Biology (Homo sapiens)
Activation of HOX genes during differentiation (Homo sapiens)
Activation of anterior HOX genes in hindbrain development during early embryogenesis (Homo sapiens)
HOXA2 chromatin is activated (Homo sapiens)
HOXA2 bivalent chromatin [nucleoplasm] (Homo sapiens)
Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
HOXA3 chromatin is activated (Homo sapiens)
HOXA3 bivalent chromatin [nucleoplasm] (Homo sapiens)
Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
HOXB2 chromatin is activated (Homo sapiens)
HOXB2 bivalent chromatin [nucleoplasm] (Homo sapiens)
Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
HOXB3 chromatin is activated (Homo sapiens)
HOXB3 bivalent chromatin [nucleoplasm] (Homo sapiens)
Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
HOXC4 chromatin is activated (Homo sapiens)
HOXC4 bivalent chromatin [nucleoplasm] (Homo sapiens)
Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
HOXD1 chromatin is activated (Homo sapiens)
HOXD1 bivalent chromatin [nucleoplasm] (Homo sapiens)
Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
HOXD3 chromatin is activated (Homo sapiens)
HOXD3 bivalent chromatin [nucleoplasm] (Homo sapiens)
Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
Retinoic acid activates HOXA1 chromatin (Homo sapiens)
RARA,G:RXRA at HOXA1 bivalent chromatin [nucleoplasm] (Homo sapiens)
Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
Retinoic acid activates HOXA4 chromatin (Homo sapiens)
RARA,B:RXRA at HOXA4 bivalent chromatin [nucleoplasm] (Homo sapiens)
Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
Retinoic acid activates HOXB1 chromatin (Homo sapiens)
RARA,G:RXRA at HOXB1 bivalent chromatin [nucleoplasm] (Homo sapiens)
Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
Retinoic acid activates HOXB4 chromatin (Homo sapiens)
RARA,B:RXRA at HOXB4 bivalent chromatin [nucleoplasm] (Homo sapiens)
Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
Retinoic acid activates HOXD4 chromatin (Homo sapiens)
RARA,B:RXRA at HOXD4 bivalent chromatin [nucleoplasm] (Homo sapiens)
Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
Maternal to zygotic transition (MZT) (Homo sapiens)
Chromatin modifications during the maternal to zygotic transition (MZT) (Homo sapiens)
KDM6A (UTX) demethylates histone H3 trimethyllysine-27 (H3K27me3) (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
KDM6B (JMJD3) demethylates histone H3 trimethyllysine-27 (H3K27me3) (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
PRC2 methylates histones and DNA (Homo sapiens)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Homo sapiens)
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Homo sapiens)
PRC2:Chromatin (5-methylcytosine, H3K27me3) [nucleoplasm] (Homo sapiens)
Chromatin with hemimethylC, H3K27me3 [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
PRC2 trimethylates histone H3 at lysine-27 (Homo sapiens)
PRC2:Chromatin (H3K27me3) [nucleoplasm] (Homo sapiens)
Chromatin with trimethylated H3K27 [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
Histone H3 (H3K27me3) [nucleoplasm] (Homo sapiens)
Participants
members
Me3K28-HIST2H3A [nucleoplasm]
(Homo sapiens)
Me3K-28-H3F3A [nucleoplasm]
(Homo sapiens)
Me3K28-HIST1H3A [nucleoplasm]
(Homo sapiens)
Participates
as an input of
KDM6A (UTX) demethylates histone H3 trimethyllysine-27 (H3K27me3) (Homo sapiens)
KDM6B (JMJD3) demethylates histone H3 trimethyllysine-27 (H3K27me3) (Homo sapiens)
as a component of
Bivalent Nucleosome (H3K27me3, H3K4me3) [nucleoplasm] (Homo sapiens)
Nucleosome with H3K27me3 [nucleoplasm] (Homo sapiens)
Inferred To
Histone H3 (H3K27me3) [nucleoplasm]
(Bos taurus)
Histone H3 (H3K27me3) [nucleoplasm]
(Caenorhabditis elegans)
Histone H3 (H3K27me3) [nucleoplasm]
(Canis familiaris)
Histone H3 (H3K27me3) [nucleoplasm]
(Danio rerio)
Histone H3 (H3K27me3) [nucleoplasm]
(Drosophila melanogaster)
Histone H3 (H3K27me3) [nucleoplasm]
(Gallus gallus)
Histone H3 (H3K27me3) [nucleoplasm]
(Mus musculus)
Histone H3 (H3K27me3) [nucleoplasm]
(Rattus norvegicus)
Histone H3 (H3K27me3) [nucleoplasm]
(Saccharomyces cerevisiae)
Histone H3 (H3K27me3) [nucleoplasm]
(Schizosaccharomyces pombe)
Histone H3 (H3K27me3) [nucleoplasm]
(Sus scrofa)
H3a [nucleoplasm]
(Dictyostelium discoideum)
Homologues of Me3K28-HIST2H3A [nucleoplasm]
(Plasmodium falciparum)
Ghost homologue of Histone H3 (H3K27me3) [nucleoplasm]
(Xenopus tropicalis)
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