Reactome | MED6 [nucleoplasm]

MED6 [nucleoplasm]

Stable Identifier

R-HSA-212359

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Locations in the PathwayBrowser for interactor UniProt:Q9NX70 MED29

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External Reference Information

External Reference

UniProt:O75586 MED6

Gene Names

MED6, ARC33

Chain

chain:1-246

Reference Genes

BioGPS Gene:10001 MED6

COSMIC (genes):MED6 MED6

CTD Gene:10001 MED6

dbSNP Gene:10001 MED6

ENSEMBL:ENSG00000133997 MED6

HGNC:19970 MED6

KEGG:hsa:10001 MED6

Monarch:10001 MED6

NCBI Gene:10001 MED6

OMIM:602984 MED6

UCSC:O75586 MED6

Reference Transcript

Other Identifiers

10001

11731437_at

11731438_x_at

11751742_x_at

11759058_at

11760463_at

11760464_x_at

11760834_x_at

207078_PM_at

207078_at

207079_PM_s_at

207079_s_at

210104_PM_at

210104_at

235473_PM_at

235473_at

2922687

35430_at

35431_g_at

35432_at

3570557

3570558

3570559

3570560

3570561

3570562

3570563

3570564

3570565

3570566

3570567

3570568

3570569

3570570

3570571

3570572

3570573

3570574

3570575

3570576

3570578

71121_r_at

77825_at

7979931

83607_at

A_23_P54170

A_24_P318319

GE54692

GO:0000151

GO:0001223

GO:0003677

GO:0003712

GO:0003713

GO:0003824

GO:0005515

GO:0005634

GO:0005654

GO:0006355

GO:0006357

GO:0016020

GO:0016567

GO:0016592

GO:0016740

GO:0032968

GO:0035019

GO:0045944

GO:0051123

GO:0060261

GO:0061630

GO:0065003

GO:0070847

GO:0140096

HMNXSV003020192

HMNXSV003049976

Hs.156061.0.A1_3p_at

ILMN_1654543

PH_hs_0010060

TC14002329.hg

g3329505_3p_at

g4885480_3p_at

p33410

Participates

as a component of

as an input of

Inferred To

Med6 [nucleoplasm] (Mus musculus)

Med6 [nucleoplasm] (Rattus norvegicus)

Ghost homologue of MED6 [nucleoplasm] (Gallus gallus)

med6 [nucleoplasm] (Danio rerio)

MED6 [nucleoplasm] (Bos taurus)

MED6 [nucleoplasm] (Canis familiaris)

MED6 [nucleoplasm] (Drosophila melanogaster)

MED6 [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_001271139.1, NP_001271138.1, NP_001271140.1, NP_005457.2

ENSEMBL

ENSP00000256379, ENSP00000413343, ENST00000256379, ENSG00000133997, ENST00000430055, ENSP00000394502, ENST00000440435

OpenTargets

ENSG00000133997

HPA

ENSG00000133997-MED6

GeneCards

MED6

PRO

O75586

Pharos - Targets

O75586

GlyGen

O75586

PDB

7ENJ, 8GXS, 8GXQ, 7ENC, 7ENA, 7NVR, 7EMF, 7LBM, 8T9D, 8TRH, 8TQW

Interactors (26)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BTT4 MED10	1	MED10 [nucleoplasm] (R-HSA-212410)	0.867	10
UniProt:P49336 CDK8	1	CDK8 [nucleoplasm] (R-HSA-212440)	0.802	9
UniProt:Q9NX70 MED29	1	MED29 [nucleoplasm] (R-HSA-556821)	0.802	7
UniProt:A0JLT2 MED19	1	MED19 [nucleoplasm] (R-HSA-556819)	0.788	7
UniProt:Q13503 MED21	1	MED21 [nucleoplasm] (R-HSA-212456)	0.788	7
UniProt:Q9NPJ6 MED4	1	MED4 [nucleoplasm] (R-HSA-350263)	0.745	7
UniProt:Q9NVC6 MED17	1	MED17 [nucleoplasm] (R-HSA-212401)	0.744	6
UniProt:Q9BUE0 MED18	1	MED18 [nucleoplasm] (R-HSA-556826)	0.744	6
UniProt:Q9BWU1 CDK19	1	CDK19 [nucleoplasm] (R-HSA-556782)	0.744	6
UniProt:O43513 MED7	1	MED7 [nucleoplasm] (R-HSA-212430)	0.725	5
UniProt:Q9H204 MED28	1	MED28 [nucleoplasm] (R-HSA-6804546)	0.669	5
UniProt:P24863 CCNC	1	CCNC [nucleoplasm] (R-HSA-212418)	0.643	4
UniProt:Q9H944 MED20	1	MED20 [nucleoplasm] (R-HSA-212428)	0.643	4
UniProt:Q93074 MED12	1	MED12 [nucleoplasm] (R-HSA-212343)	0.643	3
UniProt:Q9NWA0 MED9	1	MED9 [nucleoplasm] (R-HSA-556804)	0.643	4
UniProt:Q15648 MED1	1	MED1 [nucleoplasm] (R-HSA-212445)	0.643	4
UniProt:Q9ULK4 MED23	1	MED23 [nucleoplasm] (R-HSA-556823)	0.615	3
UniProt:Q6P2C8 MED27	1	MED27 [nucleoplasm] (R-HSA-556761)	0.564	4
UniProt:O75448 MED24	1	MED24 [nucleoplasm] (R-HSA-212331)	0.527	3
UniProt:O95402 MED26	1	MED26 [nucleoplasm] (R-HSA-556783)	0.527	4
UniProt:Q96HR3 MED30	1	MED30 [nucleoplasm] (R-HSA-212398)	0.527	2
UniProt:O15514 POLR2D	1	POLR2D [nucleoplasm] (R-HSA-63508)	0.527	2
UniProt:Q15528 MED22	1	MED22 [nucleoplasm] (R-HSA-556779)	0.527	3
UniProt:P19388 POLR2E	2	POLR2E [cytosol] (R-HSA-1964438) POLR2E [nucleoplasm] (R-HSA-83713)	0.527	2
UniProt:O15392 BIRC5	3	BIRC5 [cytosol] (R-HSA-50851) BIRC5 [nucleoplasm] (R-HSA-4655344) ub-BIRC5 [cytosol] (R-HSA-8955933)	0.527	2
UniProt:Q9Y3C7 MED31	1	MED31 [nucleoplasm] (R-HSA-212429)	0.527	3

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